Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries

Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
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DOI:
10.1155/2009/398767
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发表时间:
2009-01-01
影响因子:
2.2
通讯作者:
Cuevas, Luis Eduardo
Cuevas, Luis Eduardo
中科院分区:
医学4区
文献类型:
--
作者:
Ramsay, Andy;Yassin, Mohammed Ahmed;Cuevas, Luis Eduardo

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设置.埃塞俄比亚、尼泊尔、尼日利亚和也门。Objective.缩短完成痰液显微镜检查的时间。设计在4个国家招募923例慢性咳嗽患者并使用类似方案的横断面调查。采集点-晨-点痰标本。在第一次采集后1小时采集额外的痰液标本(Xspot),并比较以点-晨-点或点-Xspot-晨采集的前两份或前三份标本的产率。结果216例患者有>= 1个阳性涂片。spot-morning-spot法鉴定210例(97%),spot-Xspot-morning法鉴定210例(97%),其中前2个标本鉴定203例,前2个标本鉴定200例。两种差异均不显著。结论.完成涂片镜检的时间可以缩短。版权所有(C)2009 Andy Ramsay et al.
Setting. Ethiopia, Nepal, Nigeria, and Yemen. Objective. To reduce the time to complete sputum microscopy. Design. Cross-sectional surveys enrolling 923 patients with chronic cough in the 4 countries and using similar protocols. Spot-morning-spot sputum specimens were collected. An additional sputum specimen (Xspot) was collected one hour after the first, and the yields of the first two or the three specimens collected as spot-morning-spot or spot-Xspot-morning were compared. Results. 216 patients had >= one positive smear. 210 (97%) were identified by the spot-morning-spot, and 210 (97%) were identified by the spot-Xspot-morning specimens, with 203 and 200 identified by the first 2 specimens of each approach, respectively. Neither difference was significant. Conclusions. The time to complete smear microscopy could be reduced. Copyright (C) 2009 Andy Ramsay et al.