Wide-field Intensity Fluctuation Imaging.

Wide-field Intensity Fluctuation Imaging.
复制标题

宽视场强度波动成像。

DOI:
10.1101/2023.07.29.551117
复制
发表时间:
2023
期刊:
bioRxiv : the preprint server for biology
影响因子:
--
通讯作者:
Dunn,AndrewK
Dunn,AndrewK
中科院分区:
--
文献类型:
--
作者:
Fang,Qingwei;Tomar,Alankrit;Dunn,AndrewK

文献摘要

相似文献

时间强度波动包含关于光源和光介质相互作用的重要信息,并且通常由强度自相关函数g2(τ)表征。g2(τ)的测量是许多光学传感应用的中心课题,从天体物理学中的恒星强度干涉仪到生物医学科学中的荧光相关光谱和动态光散射的血流测量。目前,通过强度信号的高频采样可以容易地获得单个点处的g2(τ)。然而,g2(τ)的二维宽场成像仍然受到相机帧速率的限制。我们提出并证明了一种2脉冲曝光内调制方法,以突破相机的帧速率限制,并获得准2(τ)地图在宽领域与相机只有普通的帧速率。
The temporal intensity fluctuations contain important information about the light source and light-medium interaction and are typically characterized by the intensity autocorrelation function,g2(τ). The measurement ofg2(τ) is a central topic in many optical sensing applications, ranging from stellar intensity interferometer in astrophysics, to fluorescence correlation spectroscopy in biomedical sciences and blood flow measurement with dynamic light scattering. Currently,g2(τ) at a single point is readily accessible through high-frequency sampling of the intensity signal. However, two-dimensional wide-field imaging ofg2(τ) is still limited by the cameras’ frame rate. We propose and demonstrate a 2-pulse within-exposure modulation approach to break through the camera frame rate limit and obtain the quasig2(τ) map in wide field with cameras of only ordinary frame rates.