Ratcheting Myc.
Ratcheting Myc.
复制标题
棘轮 Myc。
DOI:
10.1016/j.ccr.2008.11.008
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发表时间:
2008
期刊:
影响因子:
50.3
通讯作者:
Eisenman,RobertN
中科院分区:
文献类型:
--
作者:
Freie,BrianW;Eisenman,RobertN
In this issue ofCancer Cell, Murphy et al. describe a mouse model designed to examine the biological effects of different levels of deregulated c-mycexpression. They provide evidence that distinct threshold levels of Myc are required for increased proliferation and for apoptosis in different tissues.