Spectrum of cardiovascular lesions in mucocutaneous lymph node syndrome: analysis of eight cases.
Spectrum of cardiovascular lesions in mucocutaneous lymph node syndrome: analysis of eight cases.
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皮肤粘膜淋巴结综合征心血管病变谱：八例分析。
DOI：
10.1016/0002-9149(80)90226-x
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Dan G. McNamara
中科院分区：
文献类型：
--
作者：
J. Fukushige;M. Nihill;Dan G. McNamara
本文报告8例皮肤粘膜淋巴结综合征合并心血管并发症。除一名患者外，所有患者的临床表现均符合上述综合征的特征。5例患者心脏扩大，6例心电图异常，3例二尖瓣关闭不全杂音。死亡的四名患者都患有冠状动脉瘤，通常与组织血栓有关。除冠状动脉受累外，在个别病例中，肾动脉、肠系膜动脉、椎动脉、脾动脉、肝动脉和髂动脉也受到影响。一名患者需要三重冠状动脉搭桥手术，一名患者接受切除肱动脉瘤。对从急性期存活下来的患者进行进一步的长期随访研究，以确定晚期并发症和后遗症的范围。
Eight cases of mucocutaneous lymph node syndrome with cardiovascular complications are described. The clinical presentation in all but one patient conformed to the previously described features of this syndrome. Five patients had cardiac enlargement, six had electrocardiographic abnormalities and three had a murmur of mitral insufficiency. Each of the four patients who died had aneurysms of the coronary arteries, usually associated with organizing thrombi. In addition to involvement of the coronary arteries, the renal, mesenteric, vertebral, splenic, hepatic and iliac arteries were affected in individual cases. One patient required triple aortocoronary bypass surgery and one patient underwent excision of a brachial arterial aneurysm. Further long-term follow-up studies of the patients who have survived the acute stage of the syndrome are indicated to establish the spectrum of late complications and sequelae.