Systematic review of research focused on pregnant and postpartum women living with HIV: A relational ethics perspective.
Systematic review of research focused on pregnant and postpartum women living with HIV: A relational ethics perspective.
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DOI：
10.1111/bioe.12917
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发表时间：
2021-10
期刊：
影响因子：
2.2
通讯作者：
Pellowski, Jennifer A.
中科院分区：
文献类型：
--
作者：
Weber, Alison Z.;Harrison, Abigail;Pellowski, Jennifer A.
从历史上看，孕产妇艾滋病毒研究的重点是预防母婴传播和儿童后果，很少关注母亲的健康后果。在艾滋病毒流行的过程中，将孕妇纳入研究的方法发生了变化。目前的情况适合审查这项研究的公共卫生伦理。本系统综述旨在确定将感染艾滋病毒的孕妇和产后妇女纳入治疗依从性和保留性研究的伦理障碍和考虑因素。我们根据PRISMA指南完成了系统的文献综述，并使用关系伦理学的角度进行了分析。纳入的研究（k=7）确定了以下方面的伦理障碍：(1)女性研究参与者作为个体，(2)伴侣和家庭动态，(3)社区对研究设计和行为的看法，以及(4)政策和监管影响。这些更广泛的背景因素将产生响应并尊重感染艾滋病毒的孕妇和产后妇女需求的研究。虽然目前的监管和政策环境可能变化缓慢，但现在可以采取行动，促进有利的研究环境。我们建议，对公共卫生伦理采取一种相关的方法，可以最好地支持感染艾滋病毒的孕妇和产后妇女的需求；承认这一人口在系统上处于不利地位，与其社区密不可分，将最有助于这一人口的健康。
Historically, maternal HIV research has focused on prevention of mother-to-child transmission and child outcomes, with little focus on the health outcomes of mothers. Over the course of the HIV epidemic, the approach to including pregnant women in research has shifted. The current landscape lends itself to reviewing the public health ethics of this research. This systematic review aims to identify ethical barriers and considerations for including pregnant and postpartum women living with HIV in treatment adherence and retention research. We completed a systematic literature review following PRISMA guidelines with analysis using a relational ethics perspective. The included studies (k=7) identified ethical barriers related to (1) women research participants as individuals, (2) partner and family dynamics, (3) community perspectives on research design and conduct, and (4) policy and regulatory implications. These broader contextual factors will yield research responsive to, and respectful of, the needs of pregnant and postpartum women living with HIV. While current regulatory and policy environments may be slow to change, actions can be taken now to foster enabling environments for research. We suggest that a relational approach to public health ethics can best support the needs of pregnant and postpartum women living with HIV; acknowledging this population as systematically disadvantaged and inseparable from their communities will best support the health of this population.
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影响因子：
2.1
作者：
Baylis, Francoise;Kenny, Nuala P.;Sherwin, Susan
通讯作者：
Sherwin, Susan
影响因子：
15.8
作者：
Johnson LF;Mossong J;Dorrington RE;Schomaker M;Hoffmann CJ;Keiser O;Fox MP;Wood R;Prozesky H;Giddy J;Garone DB;Cornell M;Egger M;Boulle A;International Epidemiologic Databases to Evaluate AIDS Southern Africa Collaboration
通讯作者：
International Epidemiologic Databases to Evaluate AIDS Southern Africa Collaboration
影响因子：
1.7
作者：
Brewster, David
通讯作者：
Brewster, David
DOI：
10.1177/1556264618783834
发表时间：
2018-10-01
影响因子：
1.3
作者：
Sullivan, Kristen A.;Little, Maggie;Lyerly, Anne Drapkin
通讯作者：
Lyerly, Anne Drapkin
影响因子：
5.4
作者：
Bennetts, A;Shaffer, N;Clark, L
通讯作者：
Clark, L