Overnight verbal memory retention correlates with the number of sleep spindles
Overnight verbal memory retention correlates with the number of sleep spindles
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DOI：
10.1016/j.neuroscience.2005.01.011
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发表时间：
2005-01-01
期刊：
影响因子：
3.3
通讯作者：
Halász, P
中科院分区：
文献类型：
--
作者：
Clemens, Z;Fabó, D;Halász, P
尽管有强有力的证据支持睡眠在巩固新获得的陈述性记忆中的作用，但特定睡眠阶段的贡献仍然存在争议。基于动物的电生理学研究，同步睡眠振荡长期以来一直被认为是睡眠相关记忆改善的可能根源。然而，迄今为止还没有研究直接调查睡眠波动对人类夜间记忆保留的影响。在本研究中，我们提供的证据表明，夜间言语记忆保留与自动算法检测到的左额中央区域的睡眠纺锤波数量高度相关。同时，发现新学习的面孔的过夜保留与纺锤体活动无关，但与非快速眼动睡眠时间相关。这些数据有力地支持了睡眠纺锤波活动与言语记忆巩固之间存在联系的理论。 (c) 2005 年由 Elsevier Ltd 代表 IBRO 出版。
Despite strong evidence supporting a role for sleep in the consolidation of newly acquired declarative memories, the contribution of specific sleep stages remains controversial. Based on electrophysiological studies in animals, synchronous sleep oscillations have been long proposed as possible origins of sleep-related memory improvement. Nevertheless, no studies to date have directly investigated the impact of sleep oscillations on overnight memory retention in humans. In the present study we provide evidence that overnight verbal memory retention is highly correlated with the number of sleep spindles detected by an automatic algorithm over left frontocentral areas. At the same time, overnight retention of newly learned faces was found to be independent of spindle activity but correlated with nonrapid-eye-movement sleep time. The data strongly support theories suggesting a link between sleep spindle activity and verbal memory consolidation. (c) 2005 Published by Elsevier Ltd on behalf of IBRO.