Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice.
Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice.
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氧自由基参与H5N1病毒引起的小鼠急性肺损伤
DOI：
10.1111/irv.12067
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发表时间：
2013-11
影响因子：
4.4
通讯作者：
Qiao J
中科院分区：
文献类型：
--
作者：
He G;Dong C;Luan Z;McAllan BM;Xu T;Zhao L;Qiao J
急性肺损伤是H5N1感染者死亡的一个重要原因。已经发现，在流感病毒感染期间，肺组织中的氧自由基（OFR）升高。在本研究中，我们使用小鼠模型来探讨OFR在H5N1病毒感染引起的急性肺损伤中的作用。
Acute lung injury is an important cause of death in humans infected with H5N1. It has been found that oxygen free radicals (OFRs) are elevated in lung tissue during influenza virus infections. In this study, we used a mouse model to explore the role of OFRs in acute lung injury caused by H5N1 viral infection.