Effectiveness of a Multifactorial Intervention in the First 1000 Days of Life to Prevent Obesity and Overweight in Childhood: Study Protocol
Effectiveness of a Multifactorial Intervention in the First 1000 Days of Life to Prevent Obesity and Overweight in Childhood: Study Protocol
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DOI：
10.3390/ijerph17072239
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发表时间：
2020-04-01
影响因子：
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通讯作者：
Ferriz-Mas, Bernardo C.
中科院分区：
文献类型：
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作者：
Diaz-Rodriguez, Mercedes;Perez-Munoz, Celia;Ferriz-Mas, Bernardo C.
(1)背景资料：肥胖是一个全球性的健康问题，预防肥胖必须成为公共卫生的优先目标，特别是考虑到儿童肥胖问题的严重性。众所周知，胎儿和出生后早期的环境可能有利于在以后的生活中出现肥胖。近年来，预防儿童肥胖的计划的影响很少。本研究的目的是评估基于早期规划概念的干预措施的有效性。(2)方法：非随机对照试验设计。入选标准为：2岁婴儿，其妊娠期开始于干预开始后的14个月内，其母亲在研究的同一临床单位对其妊娠进行了完整的随访。干预措施将针对所有已知的影响早期编程的因素，在怀孕期间长达2年的生活。儿科医生将通过数据收集表收集数据。将对数据进行单变量和多变量分析。(3)伦理和传播：试验不涉及对参与者及其后代的任何风险。获得所有参与者签署的知情同意书。已获得伦理批准。(4)结果如下：预计这项研究将提供证据，说明从生命的前1000天的关键时期预防肥胖的重要性，能够将其确立为初级保健的标准干预措施。
(1) Background: Obesity is a global health problem, and its prevention must be a priority goal of public health, especially considering the seriousness of the problem among children. It is known that fetal and early postnatal environments may favor the appearance of obesity in later life. In recent years, the impact of the programs to prevent obesity in childhood has been scarce. The aim of this research is to evaluate the effectiveness of an intervention based on the concept of early programming. (2) Methods: Non-randomized controlled trial design. Inclusion criteria are: two-year-old infants whose gestational period begins in the 14 months following the start of the intervention, and whose mothers have made the complete follow-up of their pregnancy in the same clinical unit of the study. The intervention will be developed over all the known factors that affect early programming, during pregnancy up to 2 years of life. Data will be collected through a data collection sheet by the paediatricians. A unibivariate and multivariate analysis of the data will be carried out. (3) Ethics and dissemination: The trial does not involve any risk to participants and their offspring. Signed informed consent is obtained from all participants. Ethical approval has been obtained. (4) Results: It is expected that this study will provide evidence on the importance of the prevention of obesity from the critical period of the first 1000 days of life, being able to establish this as a standard intervention in primary care.