Clinical Research of Acupuncture on Malignant Tumor Patients for Improving Depression and Sleep Quality
Clinical Research of Acupuncture on Malignant Tumor Patients for Improving Depression and Sleep Quality
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DOI：
10.1016/s0254-6272(11)60042-3
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发表时间：
2011-09-01
影响因子：
2.6
通讯作者：
Zhang Zhao
中科院分区：
文献类型：
--
作者：
Feng Yu;Wang Xin-yu;Zhang Zhao
目的：为探讨针刺治疗恶性肿瘤患者抑郁失眠的疗效，将80例恶性肿瘤患者随机分为治疗组（针刺组）和对照组（氟西汀组），每组40例。治疗30 d后采用抑郁自评量表（SDS）、汉密顿抑郁量表（HAMD）、匹兹堡睡眠质量指数（PSQI）进行评定。治疗前试验组SDS和HAMD评分分别为64.12 ± 5.34和20.92 ± 2.38，对照组64.24 ± 4.98分和20.72 ± 2.74分，治疗组治疗后SDS和HAMD评分分别为43.64 ± 5.28分和9.88 ± 1.27分，显著低于对照组（分别为50.76 ± 5.42和13.72 ± 2.05，P均< 0.05）。治疗前试验组和对照组PSQI评分分别为14.48 ± 1.71和13.92 ± 2.59，治疗后试验组PSQI评分为7.92 ± 1.22，显著低于对照组结论：针刺能有效减轻恶性肿瘤患者的抑郁情绪，改善睡眠质量，有助于提高癌症患者的生活质量。
Objective: To study the effect of acupuncture on depression and insomnia of malignant tumor patients.Methods: Eighty cases of cancer related depression and sleep disorders were randomly divided into 2 groups: treatmentl group (acupuncture n=40) and control group (Fluoxetione n=40). All patients were assessed by Self-rating Depression Scale (SDS), Hemilton Depression Rating Scale (HAMD) and Pittsburgh Sleep Quality Index (PSQI) after treatment for 30 days.Results: Before treatment the SDS and HAMD scores of the trial group were 64.12 +/- 5.34 and 20.92 +/- 2.38, those of the control group were 64.24 +/- 4.98 and 20.72 +/- 2.74, after treatment the SDS and HAMD scores of the trial group were 43.64 +/- 5.28 and 9.88 +/- 1.27 respectively, significantly lower than those of the control group (50.76 +/- 5.42 and 13.72 +/- 2.05 respectively, both P < 0.05). Before treatment the PSQI score of the trial group and the control group were 14.48 +/- 1.71 and 13.92 +/- 2.59, after treatment the PSQI score of the trial group was 7.92 +/- 1.22 after treatment, significantly lower than those of the control group (11.44 +/- 1.89, P < 0.01).Conclusion: Acupuncture can effectively reduce malignant-related depression, improve sleep quality, and help to improve the quality of life of cancer patients.