The impact of emphysema on surgical outcomes of early-stage lung cancer: a retrospective study
The impact of emphysema on surgical outcomes of early-stage lung cancer: a retrospective study
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DOI：
10.1186/s12890-019-0839-1
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发表时间：
2019-04-04
影响因子：
3.1
通讯作者：
Tsuchida, Masanori
中科院分区：
文献类型：
--
作者：
Sato, Seijiro;Nakamura, Masaya;Tsuchida, Masanori
背景CT显示肺气肿与肺癌发病率增高有关，但肺气肿患者的术后结果尚不清楚。本研究的目的是探讨肺气肿的程度和长期的结果之间的关联，以及死亡率和术后并发症，在早期肺癌患者肺切除术后。MethodsThe临床记录的566例连续肺癌患者进行肺切除术在我们的部门进行了回顾性分析。其中，364例病理I期患者的数据集可用。研究肺气肿程度与长期预后和术后并发症之间的关系。根据半定量CT评估肺气肿。根据Clavien-Dindo分类的II级手术相关并发症包括在本study.Results63例肺气肿。非肺气肿组和肺气肿组的5年总生存率和无复发生存率分别为89.0%和61.3%（P
BackgroundThe presence of emphysema on computed tomography (CT) is associated with an increased frequency of lung cancer, but the postoperative outcomes of patients with pulmonary emphysema are not well known. The objective of this study was to investigate the association between the extent of emphysema and long-term outcomes, as well as mortality and postoperative complications, in early-stage lung cancer patients after pulmonary resection.MethodsThe clinical records of 566 consecutive lung cancer patients who underwent pulmonary resection in our department were retrospectively reviewed. Among these, the data sets of 364 pathological stage I patients were available. The associations between the extent of lung emphysema and long-term outcomes and postoperative complications were investigated. Emphysema was assessed on the basis of semiquantitative CT. Surgery-related complications of GradeII according to the Clavien-Dindo classification were included in this study.ResultsEmphysema was present in 63 patients. The overall survival and relapse-free survival of the non-emphysema and emphysema groups at 5 years were 89.0 and 61.3% (P