The QT interval during reflex cardiovascular adaptation.

The QT interval during reflex cardiovascular adaptation.
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反射性心血管适应过程中的 QT 间期。

DOI:
10.1161/01.cir.69.1.22
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发表时间:
1984
期刊:
影响因子:
37.8
通讯作者:
Stewart Wolf
Stewart Wolf
中科院分区:
医学1区
文献类型:
--
作者:
T. A. Davidowski;Stewart Wolf

文献摘要

被引文献

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我们研究了健康受试者在运动后以及屏气、过度换气、潜水反射、瓦氏动作和冷加压试验期间心率变化与心电图 QT 间期测量之间的关系。运动时的心动过速伴随着我们所熟悉的 QT 间期缩短,但在其他更“久坐”的运动中遇到的大幅心率变化却伴随着 QT 间期的非常小的变化。因此,在后一种情况下计算校正的 QT 会产生虚假结果。数据表明,心率对 QT 间期的直接影响即使有,也非常小。健康受试者的间隔时间长短似乎很大程度上是由反射引起的离散自主神经影响决定的。与运动相关的那些会导致 QT 缩短,但在不涉及运动的神经介导的心血管调节过程中,QT 保持在狭窄的范围内。
We examined the relationship between changes in heart rate and the measured QT interval of the electrocardiogram in healthy subjects after exercise and during breath holding, hyperventilation, the dive reflex, the Valsalva maneuver, and the cold-pressor test. The tachycardia of exercise was accompanied by the familiar shortening of the QT interval, but substantial heart rate changes encountered in other more "sedentary" maneuvers were accompanied by very small changes in QT. Calculating the corrected QT in the latter instances, therefore, yielded spurious results. The data suggest very little, if any, direct effect of heart rate on the QT interval. The length of the interval in healthy subjects appears to be determined largely by reflexly elicited discrete autonomic influences. Those associated with exercise result in QT shortening but, during neurally mediated cardiovascular adjustments that do not involve exercise, QT is maintained within narrow limits.