Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: Concurrent expression in cancer cells from primary tumour and metastatic lymph node
Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: Concurrent expression in cancer cells from primary tumour and metastatic lymph node
复制标题
DOI：
10.1016/j.lungcan.2007.06.021
复制
发表时间：
2007-11-01
期刊：
影响因子：
5.3
通讯作者：
Kraemer, Michel
中科院分区：
文献类型：
--
作者：
Saintigny, Pierre;Kambouchner, Marianne;Kraemer, Michel
简介：血管内皮生长因子-C（VEGF-C）和血管内皮生长因子受体-3（VEGFR-3）在非小细胞肺癌（NSCLC）中的作用的研究主要集中在与淋巴管生成相关的淋巴结（LN）转移。然而，肿瘤细胞共表达VEGF-C/VEGFR-3可以独立地发挥重要作用。
Introduction: Investigation of the role of vascular endothelial growth factor-C (VEGF-C) and VEGF receptor-3 (VEGFR-3) in non-small-cell lung cancer (NSCLC) has mainly focused on lymph node (LN) metastasis related to lymphangiogenesis. However, the coexpression of VEGF-C/VEGFR-3 by tumour cells can independently play an important role.