Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19)
Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19)
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DOI：
10.1097/a0g.0000000000003949
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发表时间：
2020-07-01
影响因子：
7.2
通讯作者：
Gaw, Stephanie L.
中科院分区：
文献类型：
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作者：
Blauvelt, Christine A.;Chiu, Catherine;Gaw, Stephanie L.
背景技术背景：数据表明，与非妊娠患者相比，妊娠女性感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）或发生严重疾病的风险并没有增加。然而，对2019冠状病毒病（COVID-19）感染重症孕妇的管理因生理变化和其他妊娠考虑因素而复杂化，需要平衡母体和胎儿的健康。案例：我们报告了一例妊娠28周时因COVID-19感染而患急性呼吸窘迫综合征（ARDS）的患者，其呼吸状况恶化促使分娩。我们的病人的氧合和呼吸力学在分娩后几个小时内得到改善，尽管她需要长时间的机械通气，直到产后第10天。新生儿拭子SARS-CoV-2和COVID-19免疫球蛋白（IG）G和IgM均为阴性。结论：我们描述了我们对COVID-19感染所致的早产儿ARDS患者及其新生儿的多学科管理。
BACKGROUND: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being. CASE: We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative. CONCLUSION: We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.