Separation of nanoparticles by gel electrophoresis according to size-and shape
Separation of nanoparticles by gel electrophoresis according to size-and shape
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DOI：
10.1021/nl071615y
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发表时间：
2007-09-01
期刊：
影响因子：
10.8
通讯作者：
Sonnichsen, Carsten
中科院分区：
文献类型：
--
作者：
Hanauer, Matthias;Pierrat, Sebastien;Sonnichsen, Carsten
我们展示了金和银纳米粒子包覆一层带电聚合物后，通过琼脂糖凝胶电泳法根据其大小和形状进行分离的方法。利用贵金属颗粒的大小和形状相关的等离子体共振对这种分离进行光学监测，并通过透射电子显微镜(TEM)进行确认。基于亨利公式的模型定量解释了凝胶迁移率，为预测聚合物包覆纳米粒子的凝胶迁移率提供了理论框架。
We demonstrate the separation of gold and silver nanoparticles according to their size and shape by agarose gel electrophoresis after coating them with a charged polymer layer. The separation is monitored optically using the size- and shape-dependent plasmon resonance of noble metal particles and confirmed by transmission electron microscopy (TEM). Electrophoretic mobilities are quantitatively explained by a model based on the Henry formula; providing a theoretical framework for predicting gel mobilities of polymer coated nanoparticles.