Association of obesity with postacute sequelae of COVID-19
Association of obesity with postacute sequelae of COVID-19
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DOI：
10.1111/dom.14454
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发表时间：
2021-06-15
影响因子：
5.8
通讯作者：
Burguera, Bartolome
中科院分区：
文献类型：
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作者：
Aminian, Ali;Bena, James;Burguera, Bartolome
肥胖是发展为严重冠状病毒病2019(新冠肺炎)感染和死亡的主要风险因素。然而，目前尚不清楚肥胖患者患新冠肺炎急性后遗症的风险是否更大。在2,839名不需要入院重症监护病房并度过新冠肺炎急性期的患者的病毒检测呈阳性后30天起的中位时间8个月的随访中，1,230例(43%)患者需要进行医学诊断测试，1,255例(44%)患者入院，29例(1%)患者死亡。与体重指数(BMI)正常的患者相比，中度和重度肥胖患者的住院风险分别高出28%和30%。与体重指数正常的患者相比，中度和重度肥胖患者对诊断测试评估不同医疗问题的需求分别高出25%和39%。这项研究的结果表明，中度和重度肥胖(BMI和Gt；=35 kg/m(2))与患PASC的风险更大相关。
Obesity is a major risk factor for the development of severe coronavirus disease 2019 (COVID-19) infection and mortality. However, it is not known whether patients with obesity are at a greater risk of developing postacute sequelae of COVID-19 (PASC). In a median follow-up time of 8 months and counting from 30 days following a positive viral test of 2839 patients who did not require intensive care unit admission and survived the acute phase of COVID-19, 1230 (43%) patients required medical diagnostic tests, 1255 (44%) patients underwent hospital admission, and 29 (1%) patients died. Compared with patients with a normal body mass index (BMI), the risk of hospital admission was 28% and 30% higher in patients with moderate and severe obesity, respectively. The need for diagnostic tests to assess different medical problems, compared with patients with normal BMI, was 25% and 39% higher in patients with moderate and severe obesity, respectively. The findings of this study suggest that moderate and severe obesity (BMI >= 35 kg/m(2)) are associated with a greater risk of PASC.