National Serologic Survey of Haematobium Schistosomiasis in Morocco Evidence for Elimination
National Serologic Survey of Haematobium Schistosomiasis in Morocco Evidence for Elimination
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DOI：
10.4269/ajtmh.2011.10-0378
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发表时间：
2011-01-01
影响因子：
3.3
通讯作者：
Rhajaoui, Mohamed
中科院分区：
文献类型：
--
作者：
Amarir, Fatima;El Mansouri, Bouchra;Rhajaoui, Mohamed
摩洛哥卫生部于1994年启动了消除血吸虫病的进程。在2005-2009年期间，流行病学状况显示，在国家一级，疾病传播明显中断，只有少数残留病例被记录。我们目前的研究是第一次系统的血清学调查，以评估剩余疾病地方病疫源地的传播状况。从有血吸虫病高传播史的省份中选择了382名在最后一个本地病例发生日期之后出生的儿童（Tata，Chtouka Ait Baha埃拉奇迪亚El Kelaa Des Sraghna，和贝尼Mellal）为了鉴定针对埃及血吸虫成虫微粒体抗原的疾病特异性抗体的存在，通过使用一种酶-结果表明，所有血吸虫病患者血清中均未检测到血吸虫病抗体。因此，我们的研究结果证实，在最后一个流行区内，血吸虫病的传播处于低水平或中断状态
The Moroccan Health Ministry launched a Process of Eliminating Schistosomiasis in 1994 During 2005-2009, the epidemiologic status showed a clear interruption of disease transmission at the national level, only a few residual cases were recorded Our present study is the first systematic serologic survey to evaluate the transmission status in remaining disease endemic foci A study population of 2,382 children born after the date of the last autochthonous cases were selected from provinces with histories of high schistosomiasis transmission (Tata, Chtouka Ait Baha Errachidia El Kelaa Des Sraghna, and Beni Mellal) To identify the presence of disease specific antibodies directed against Schistosoma haematobium adult worm microsomal antigens were detected by using an enzyme-linked immunoelectrotransfer blot assay The results showed an absence of antibodies in all serum samples Consequently, our findings confirm either a low transmission status or an interruption of schistosomiasis transmission within the last disease endemic foci