Seroprevalence and Associated Risk Factors for Toxoplasma gondii Infection in Healthy Blood Donors: A Cross-Sectional Study in Sonora, Mexico.
Seroprevalence and Associated Risk Factors for Toxoplasma gondii Infection in Healthy Blood Donors: A Cross-Sectional Study in Sonora, Mexico.
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健康献血者弓形虫感染的血清阳性率和相关危险因素：墨西哥索诺拉州的一项横断面研究。
DOI：
10.1155/2016/9597276
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发表时间：
2016
影响因子：
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通讯作者：
Liesenfeld O
中科院分区：
文献类型：
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作者：
Alvarado-Esquivel C;Rascón-Careaga A;Hernández-Tinoco J;Corella-Madueño MA;Sánchez-Anguiano LF;Aldana-Madrid ML;Velasquez-Vega E;Quizán-Plata T;Navarro-Henze JL;Badell-Luzardo JA;Gastélum-Cano JM;Liesenfeld O
刚地弓形虫可通过输血传播。我们确定了墨西哥埃莫西约市健康献血者中弓形虫感染的流行程度，以及弓形虫感染与献血者的社会人口学、临床和行为特征之间的关系。在埃莫西约市的两个公共血库，对480名献血者进行了抗t检测。采用酶联免疫法检测弓形虫IgG和IgM抗体。408例献血者（平均年龄31.77±9.52岁，18 ~ 60岁）中，55例（13.5%）抗t抗体阳性。弓形虫IgG抗体，12例（21.8%）抗体阳性。弓形虫IgM抗体多因素分析显示，弓形虫血清阳性与年龄（OR = 1.74; 95% CI: 1.03-2.94; P = 0.03）和吸烟（OR = 2.09; 95% CI: 1.02-4.29; P = 0.04）有关。弓形虫血清阳性与妊娠、分娩和剖宫产次数相关。索诺拉献血者中弓形虫感染的血清流行率是迄今为止墨西哥北部献血者中报告的最高的。这是关于弓形虫接触与烟草使用之间关系的第一份报告。需要进一步的研究来证实这种联系。
Toxoplasma gondii (T. gondii) can be transmitted by blood transfusion. We determined the prevalence of T. gondii infection in healthy blood donors in Hermosillo city, Mexico, and the association of infection with T. gondii with the sociodemographic, clinical, and behavioral characteristics of blood donors. Four hundred and eight blood donors who attended two public blood banks in Hermosillo city were examined for anti-T. gondii IgG and IgM antibodies by using enzyme-linked immunoassays. Of the 408 blood donors (mean age 31.77 ± 9.52; range 18–60 years old) studied, 55 (13.5%) were positive for anti-T. gondii IgG antibodies, and 12 (21.8%) of them were also positive for anti-T. gondii IgM antibodies. Multivariate analysis showed that seropositivity to T. gondii was associated with age (OR = 1.74; 95% CI: 1.03–2.94; P = 0.03) and tobacco use (OR = 2.09; 95% CI: 1.02–4.29; P = 0.04). Seropositivity to T. gondii was correlated with the number of pregnancies, deliveries, and cesarean sections. The seroprevalence of T. gondii infection in blood donors in Sonora is the highest reported in blood donors in northern Mexico so far. This is the first report of an association of T. gondii exposure and tobacco use. Further research to confirm this association is needed.