Cytoarchitectural maps of the human brain in standard anatomical space
Cytoarchitectural maps of the human brain in standard anatomical space
复制标题
标准解剖空间中人脑的细胞结构图
作者：
P. Roland;S. Geyer;K. Amunts;T. Schormann;A. Schleicher;Aleksander Malikovic;K. Zilles
人类大脑皮层显著的主体间可变性为功能-结构关系的系统研究提出了重大问题。大脑之间缺乏同源性和宏观标志意味着人们无法在三维或二维空间中找到一个脑回或脑沟的哪个部分与另一个受试者的大脑皮层的哪个部分相匹配。此外，细胞结构边界和沟底之间经常缺乏对应关系，使大体形态和微观结构之间的相关性失效。因此，我们提出应该使用微观结构标准来定义一个解剖空间，以便对个体大脑进行比较，并通过定量手段为每个细胞结构定义的区域建立概率图[Roland and Zilles, 1994；神经科学进展[17]。在这里，我们检查了细胞建筑区域4a， 4p, 3a, 3b， V1和V2到两个常用的解剖标准参考空间的映射。对Talairach空间的线性全局变换产生了相应细胞结构区域的最小重叠。将全局仿射和非仿射转换到人脑图谱（HBA）的解剖空间中，相应的细胞结构区域的重叠量显著增加。期望局部变换可以进一步改善相应细胞结构区域的配准，从而定义一个共同的标准解剖空间，研究大体解剖结构和功能的变化。嗡嗡声。Brain Mapping 5:222-227, 1997。©1997 Wiley‐Liss, Inc。
The remarkable intersubject variability of the human cerebral cortex poses major problems for the systematic study of functional‐structural relationships. Lack of homology and macroscopical landmarks between brains implies that one cannot in three or two dimensions find which part of one gyrus or sulcus matches which part of another subject's cerebral cortex. Furthermore, the frequent lack of correspondence between cytoarchitectural borders and the bottom of sulci invalidates correlations between gross morphology and microstructure. Therefore, we proposed that microstructural criteria should be used to define an anatomical space for comparison of individual brains and for establishing a probability map for each cytoarchitecturally defined area by quantitative means [Roland and Zilles, 1994; Trends Neurosci 17:458–467]. Here we examined the mapping of cytoarchitectural areas 4a, 4p, 3a, 3b, V1, and V2 into two commonly used anatomical standard reference spaces. Linear global transformations into Talairach space produced minimal overlap of corresponding cytoarchitectural areas. Global affine and nonaffine transformations into the anatomical space of the Human Brain Atlas (HBA) gave significantly larger volumes of overlap of corresponding cytoarchitectural areas. It is expected that local transformations can further improve the registration of corresponding cytoarchitectural areas and thereby define a common standard anatomical space in which to study variations in gross anatomical structure and function. Hum. Brain Mapping 5:222–227, 1997. © 1997 Wiley‐Liss, Inc.
影响因子：
1.3
作者：
Davatzikos, C
通讯作者：
Davatzikos, C