Poor-quality sleep score is an independent predictor of nondipping hypertension
Poor-quality sleep score is an independent predictor of nondipping hypertension
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DOI：
10.1097/mbp.0b013e32833a23a0
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发表时间：
2010-08-01
影响因子：
1.3
通讯作者：
Alemdar, Recai
中科院分区：
文献类型：
--
作者：
Erden, Ismail;Erden, Emine Cakcak;Alemdar, Recai
目的 我们旨在调查初次诊断为高血压的相对年轻患者的非浸渍状态与睡眠质量之间是否存在关联。方法 连续 133 名经主治医生诊断为 1 期高血压的患者被转介至我们的研究中。有任何抗高血压药物使用史的患者被排除在外。符合条件的患者接受了匹兹堡睡眠质量指数（PSQI）调查，该调查在评估睡眠障碍方面具有明确的作用。所有患者均接受动态血压监测。 结果 非杓型高血压患者 71 例（平均年龄 44.3 +/- 5.3 岁，男性 33 例/女性 38 例），杓型高血压患者 62 例（平均年龄 43.3 +/- 6.3 岁，男性 27 例/女性 35 例）。在全球范围内，非杓型人群的 PSQI 得分显着高于杓型人群。人们注意到，非杓型人的 PSQI 的所有组成部分（睡眠质量、睡眠潜伏期、睡眠持续时间、睡眠效率、睡眠障碍、安眠药物的使用和日间功能障碍）均显着较高。相关分析显示，夜间收缩压下降与PSQI呈显着负相关（r = -0.46，P < 0.001）。 Logistic 回归分析显示，PSQI 评分是非倾斜性高血压 (HT) 的独立决定因素{优势比 = 0.842 [95% 置信区间 (CI) = 0.748-0.947； P = 0.004]}。结论 我们表明，睡眠质量差与非浸渍模式相关，此外，它是新诊断的 1 期高血压患者非浸渍的独立预测因子 Blood Press Monit 15:184-187 (C) 2010 Wolters Kluwer Health 垂直条 Lippincott Williams & Wilkins。
Objective We aimed to investigate whether there was any association between the nondipping status and sleep quality in relatively young patients with an initial diagnosis of hypertension.Methods One hundred and thirty-three consecutive patients, diagnosed to have stage 1 hypertension by their primary physicians, were referred to our study. Patients with a history of use of any antihypertensive medication were excluded. Eligible patients underwent the Pittsburgh Sleep Quality Index (PSQI) survey, which has an established role in evaluating sleep disturbances. All patients underwent ambulatory blood pressure monitoring.Results There were 71 nondipper patients (mean age 44.3 +/- 5.3 years, 33 male/38 female) and 62 dipper hypertensive patients (mean age 43.3 +/- 6.3 years, 27 male/35 female). The PSQI scores, globally, were significantly higher in the nondippers compared with the dippers. It was noticed that all the components of the PSQI (sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbance, use of sleep medication, and daytime dysfunction) were significantly higher in the nondippers. Correlation analysis showed that systolic blood pressure fall at night was inversely and significantly related with the PSQI (r = -0.46, P < 0.001). Logistic regression analysis showed that the PSQI score is an independent determinant for nondipping hypertension (HT) {odds ratio = 0.842 [95% confidence interval (CI) = 0.748-0.947; P = 0.004]}.Conclusion We showed that poor sleep quality was related with a nondipping pattern, and furthermore, it was an independent predictor of nondipping in newly diagnosed stage 1 hypertensive patients Blood Press Monit 15:184-187 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.