Structure and evolution of the mitochondrial DNA complete control region in the Drosophila subobscura subgroup
Structure and evolution of the mitochondrial DNA complete control region in the Drosophila subobscura subgroup
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DOI：
10.1046/j.0962-1075.2001.00295.x
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发表时间：
2001-12-01
影响因子：
2.6
通讯作者：
González, AM
中科院分区：
文献类型：
--
作者：
Brehm, A;Harris, DJ;González, AM
线粒体DNA富含A+T区(MtDNA)在果蝇亚群D.subbobscura、D.madeirensis和D.Guance中已被克隆和测序。将这些序列与已发表的其他序列进行比较分析，发现了在果蝇和其他昆虫中保守的新序列基序。一个可能的双向启动子和一个停止信号被认为参与了果蝇mtDNA的初级链复制。这一区域有力地解决了系统发育分析中包括的物种之间的关系，无论是对于密切相关的物种，还是在更深的系统发育水平上，当只考虑左侧和中央区域时都是如此。
The complete A+ T-rich region of mitochondrial DNA (mtDNA) has been cloned and sequenced in the species of the Drosophila subobscura subgroup D. subobscura, D. madeirensis and D. guanche. Comparative analysis of these sequences with others already published has identified new sequence motifs that are conserved In Drosophila and other insects. A putative bi-directional promoter and a stop signal are proposed to be involved in the primary mtDNA strand replication of Drosophila. This region strongly resolves relationships of the species included in a phylogenetic analysis, both for closely related species and also at deeper phylogenetic levels when only the left and central domains are taken Into account.