Distinct prefrontal activations in processing sequence at the sentence and script level:: An fMRI study
Distinct prefrontal activations in processing sequence at the sentence and script level:: An fMRI study
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DOI：
10.1016/s0028-3932(99)00054-8
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发表时间：
1999-12-01
期刊：
影响因子：
2.6
通讯作者：
LeBihan, D
中科院分区：
文献类型：
--
作者：
Crozier, S;Sirigu, A;LeBihan, D
神经心理学研究表明，前额叶皮层在计划和监控日常行为方面非常重要。在这项研究中，使用功能磁共振成像（fMRI），我们调查是否特定的前额叶区域参与处理一系列的行动。受试者被要求执行两个不同的任务：脚本事件顺序和句子单词顺序。脚本序列和单词序列处理被发现激活部分重叠的区域，这些区域被认为与语言处理有关。此外，脚本任务激活了左侧和右侧大脑半球的背外侧前额叶皮层（Brodmann区6和8，BA 6和8）中的一个大区域，以及左侧辅助运动区和左侧角回（BA 39）。我们的研究结果表明，这些前额叶区可能更具体地参与分析的过程中的动作域的顺序链接。(C)1999爱思唯尔科技有限公司。保留所有权利。
Neuropsychological studies have shown that the prefrontal cortex is important in planning and monitoring everyday behaviour. In this study, using functional magnetic resonance imaging (fMRI), we investigated whether specific prefrontal regions are involved in processing a sequence of actions. Subjects were required to perform two different tasks: Script-event order and Sentence-word order. Script sequence and word sequence processing were found to activate partially overlapping areas which are known to be implicated in language processing. In addition, the Script-task activated a large area in the dorsolateral prefrontal cortex (Brodmann area 6 and 8, BA 6 and 8), in both the left and right hemispheres, as well as the left supplementary motor area and left angular gyrus (BA 39). Our results suggest that these prefrontal areas may be more specifically involved in the process of analysing sequential links in the action domain. (C) 1999 Elsevier Science Ltd. All rights reserved.