THE B-CELL ANTIGEN RECEPTOR COMPLEX - STRUCTURE AND SIGNAL-TRANSDUCTION

THE B-CELL ANTIGEN RECEPTOR COMPLEX - STRUCTURE AND SIGNAL-TRANSDUCTION
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DOI:
10.1016/0167-5699(94)90267-4
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发表时间:
1994-09-01
期刊:
IMMUNOLOGY TODAY
影响因子:
--
通讯作者:
CAMBIER, JC
CAMBIER, JC
中科院分区:
其他
文献类型:
--
作者:
PLEIMAN, CM;DAMBROSIO, D;CAMBIER, JC

文献摘要

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免疫反应的特异性由B细胞受体(BCR)与其同源结构抗原之间的相互作用决定。最近的研究提供了相当多的洞察功能区室化内这一极其多才多艺的异源寡聚受体复合物。在这篇文章中,Christopher Pleiman,Daniele D'Ambrosio和John Cambier巩固了关于BCR结构和信号转导的新发现。
The specificity of the immune response is determined by the interaction between the B-cell receptor (BCR) and its cogitate structure, antigen. Recent studies have provided considerable insight into the compartmentalization of function within this extremely versatile hetero-oligomeric receptor complex. In this article, Christopher Pleiman, Daniele D'Ambrosio and John Cambier consolidate new findings regarding BCR structure and signal transduction.