Large-scale changes in dendritic structure during reorganization of adult somatosensory cortex

Large-scale changes in dendritic structure during reorganization of adult somatosensory cortex
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DOI:
10.1038/nn1384
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发表时间:
2005-02-01
影响因子:
25
通讯作者:
Steen, PA
Steen, PA
中科院分区:
医学1区
文献类型:
--
作者:
Hickmott, PW;Steen, PA

文献摘要

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在成年大鼠的体感皮层(S1)中,神经元是有偏差的,并且靠近前爪和下颌表征之间的边界的树突乔木较少。感官体验的变化会导致新皮质功能组织的变化。因此,我们检查了前爪去神经后 S1 重组区域神经元的形态。我们发现,在重组过程中,树突乔木发生了变化,以反映边界的新位置。
In adult rat somatosensory cortex (S1), neurons are biased and have less dendritic arbor close to the border between the forepaw and lower jaw representations. Changes in sensory experience cause changes in the functional organization of the neocortex. Therefore, we examined the morphology of neurons in the reorganized region of S1 after forepaw denervation. We found that during reorganization dendritic arbors changed to reflect the new location of the border.