Factors associated with malaria parasitaemia, malnutrition, and anaemia among HIV-exposed and unexposed Ugandan infants: a cross-sectional survey

Factors associated with malaria parasitaemia, malnutrition, and anaemia among HIV-exposed and unexposed Ugandan infants: a cross-sectional survey
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DOI:
10.1186/1475-2875-11-432
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发表时间:
2012-12-27
期刊:
影响因子:
3
通讯作者:
Dorsey, Grant
Dorsey, Grant
中科院分区:
医学3区
文献类型:
--
作者:
Osterbauer, Beth;Kapisi, James;Dorsey, Grant

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背景:疟疾、营养不良和贫血是非洲儿童发病和死亡的主要原因。这些条件之间的相互作用是复杂的,关于未感染艾滋病毒和感染艾滋病毒的妇女所生婴儿与这些条件有关的因素的数据有限。方法:从乌干达农村疟疾高传播地区招募了200名艾滋病毒暴露者(艾滋病毒感染母亲所生的未感染艾滋病毒的婴儿)和400名未感染艾滋病毒的婴儿。在入组时进行了横断面调查,以测量疟疾寄生虫病的患病率,测量营养不良(z分数)
Background: Malaria, malnutrition and anaemia are major causes of morbidity and mortality in African children. The interplay between these conditions is complex and limited data exist on factors associated with these conditions among infants born to HIV-uninfected and infected women.Methods: Two hundred HIV-exposed (HIV-uninfected infants born to HIV-infected mothers) and 400 HIV-unexposed infants were recruited from an area of high malaria transmission in rural Uganda. A cross-sectional survey was performed at enrolment to measure the prevalence of malaria parasitaemia, measures of malnutrition (z-scores