An Update on mRNA-Based Viral Vaccines.
An Update on mRNA-Based Viral Vaccines.
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DOI:
10.3390/vaccines9090965
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发表时间:
2021-08-29
期刊:
影响因子:
7.8
通讯作者:
Kang SM
中科院分区:
文献类型:
--
作者:
Jeeva S;Kim KH;Shin CH;Wang BZ;Kang SM
With the success of COVID-19 vaccines, newly created mRNA vaccines against other infectious diseases are beginning to emerge. Here, we review the structural elements required for designing mRNA vaccine constructs for effective in vitro synthetic transcription reactions. The unprecedently speedy development of mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was enabled with previous innovations in nucleoside modifications during in vitro transcription and lipid nanoparticle delivery materials of mRNA. Recent updates are briefly described in the status of mRNA vaccines against SARS-CoV-2, influenza virus, and other viral pathogens. Unique features of mRNA vaccine platforms and future perspectives are discussed.
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影响因子:
4.1
作者:
Asrani, Kirtika H.;Farelli, Jeremiah D.;Brown, Jeffrey M.
通讯作者:
Brown, Jeffrey M.
影响因子:
4.5
作者:
Babendure, JR;Babendure, JL;Tsien, RY
通讯作者:
Tsien, RY
影响因子:
7.8
作者:
Buschmann MD;Carrasco MJ;Alishetty S;Paige M;Alameh MG;Weissman D
通讯作者:
Weissman D
DOI:
10.1056/nejmoa2035389
发表时间:
2021-02-04
期刊:
The New England journal of medicine
影响因子:
--
作者:
Baden LR;El Sahly HM;Essink B;Kotloff K;Frey S;Novak R;Diemert D;Spector SA;Rouphael N;Creech CB;McGettigan J;Khetan S;Segall N;Solis J;Brosz A;Fierro C;Schwartz H;Neuzil K;Corey L;Gilbert P;Janes H;Follmann D;Marovich M;Mascola J;Polakowski L;Ledgerwood J;Graham BS;Bennett H;Pajon R;Knightly C;Leav B;Deng W;Zhou H;Han S;Ivarsson M;Miller J;Zaks T;COVE Study Group
通讯作者:
COVE Study Group
影响因子:
5.5
作者:
Aldrich C;Leroux-Roels I;Huang KB;Bica MA;Loeliger E;Schoenborn-Kellenberger O;Walz L;Leroux-Roels G;von Sonnenburg F;Oostvogels L
通讯作者:
Oostvogels L