Microinversions in mammalian evolution
Microinversions in mammalian evolution
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DOI:
10.1073/pnas.0603984103
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发表时间:
2006-12-26
影响因子:
11.1
通讯作者:
Pevzner, P. A.
中科院分区:
文献类型:
--
作者:
Chaisson, M. J.;Raphael, B. J.;Pevzner, P. A.
We propose an approach for identifying microinversions across different species and show that microinversions provide a source of low-homoplasy evolutionary characters. These characters may be used as "certificates" to verify different branches in a phylogenetic tree, turning the challenging problem of phylogeny reconstruction into a relatively simple algorithmic problem. We estimate that there exist hundreds of thousands of microinversions in genomes of mammals from comparative sequencing projects, an untapped source of new phylogenetic characters.