Competition between multiple totally asymmetric simple exclusion processes for a finite pool of resources
Competition between multiple totally asymmetric simple exclusion processes for a finite pool of resources
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DOI：
10.1103/physreve.80.031142
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发表时间：
2009-09-01
影响因子：
2.4
通讯作者：
Schmittmann, B.
中科院分区：
文献类型：
--
作者：
Cook, L. Jonathan;Zia, R. K. P.;Schmittmann, B.
利用Monte Carlo模拟和畴壁理论，我们讨论了几个完全不对称的简单排斥过程（TASEPs）耦合到一个有限的粒子库的效果。这个简单的模型模拟了在有限资源存在下的定向生物运输过程，例如由有限的核糖体池限制的蛋白质合成。如果所有的TASEP具有相等的长度，我们发现的行为是类似于一个单一的TASEP耦合到一个有限的池。对于具有不同长度的链的更一般的情况，出现了几个未预料到的制度。一个广义畴壁理论捕捉我们的研究结果与模拟结果吻合良好。
Using Monte Carlo simulations and a domain-wall theory, we discuss the effect of coupling several totally asymmetric simple exclusion processes (TASEPs) to a finite reservoir of particles. This simple model mimics directed biological transport processes in the presence of finite resources such as protein synthesis limited by a finite pool of ribosomes. If all TASEPs have equal length, we find behavior which is analogous to a single TASEP coupled to a finite pool. For the more generic case of chains with different lengths, several unanticipated regimes emerge. A generalized domain-wall theory captures our findings in good agreement with simulation results.