A comparison of the effect of autogenous vs. frozen homogenous grafts on the healing of non-union of forearm bones.
A comparison of the effect of autogenous vs. frozen homogenous grafts on the healing of non-union of forearm bones.
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发表时间：
2008-03
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通讯作者：
Maciej Piotrowski;R. Pankowski;P. Luczkiewicz;A. Markowicz
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作者：
Maciej Piotrowski;R. Pankowski;P. Luczkiewicz;A. Markowicz
大部分自体和同质移植物被吸收并被受体自身组织替代。一般认为自体移植上级同种异体移植。本研究的目的是比较自体骨移植和同种异体骨移植在前臂骨不连愈合中的有效性。材料与方法1976年至2005年，对56例68处前臂骨不连患者进行了手术治疗，其中男45例，女11例，年龄8 ~ 85岁。采用自体松质骨片或均质冷冻移植物对患者进行手术。47例采用自体骨移植，21例采用同种异体骨移植治疗骨不连。随后比较了两种类型移植物实现骨愈合的有效性和速度。结果自体骨与同种异体骨的愈合率和愈合时间相似。差异无统计学显著性。结论：自体骨移植与同种异体骨移植的有效性和骨愈合时间无统计学显著差异。当移植物的机械优势不重要时，使用同质冷冻移植物似乎是合理的。它还可以避免对身体健康部位的额外伤害。
BACKGROUND A large percentage of autogenous and homogenous grafts are resorbed and replaced by the recipient's own tissue. It is generally believed that autogenous grafts are superior to homogenous ones. The aim of our study was to compare the effectiveness of autografts and allografts in achieving the healing of a non-union of forearm bones. MATERIAL AND METHODS Between 1976 and 2005, 56 patients with 68 non-unions of forearm bone shafts were operated on. The study group consisted of 45 male and 11 female patients aged 8 to 85. The patients were operated on using methods requiring autogenous cancellous bone chips or homogenous frozen grafts. Autografts were used in 47 patients, and allografts were applied in the treatment of 21 non-unions. The effectiveness and speed of achieving a bone union with both types of grafts were subsequently compared. RESULTS The percentage and time of bone union were similar between autogenous and homogenous grafts. The differences are not statistically significant. CONCLUSION No statistically significant differences in the effectiveness and time to bone union were found between recipients of autogenous vs. homogenous grafts. The use of homogenous frozen grafts seems justified when the mechanical advantages of the graft are not essential. It also allows for avoiding additional mutilation to healthy parts of the body.