Optical filters inhibiting television-induced photosensitive seizures

Optical filters inhibiting television-induced photosensitive seizures
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滤光片抑制电视引起的光敏癫痫发作

DOI:
10.1212/wnl.57.10.1767
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发表时间:
2001
期刊:
影响因子:
9.9
通讯作者:
N. Kondo
N. Kondo
中科院分区:
医学1区
文献类型:
--
作者:
Y. Takahashi;T. Sato;K. Goto;M. Fujino;T. Fujiwara;M. Yamaga;T. Ito;H. Isono;N. Kondo

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目的:电视图像是引起光敏感人群光敏癫痫发作的最常见刺激。为了抑制患有或未患有癫痫的光敏感人群的光敏性癫痫发作,作者寻求非药物方法来降低电视图像的光刺激水平。背景:作者发现了光阵发性反应 (PPR) 的两种病理生理机制(波长依赖性机制和光量依赖性机制)。方法:作者测试了两种不同类型的滤光片,一种选择性地反射长波长红光,这激发了波长相关的机制,另一种均匀地吸收可见光谱中的光(中性密度滤光片)。通过使用频闪灯的传统间歇光刺激(IPS)和使用闪烁阴极射线管(CRT)的新型光刺激来研究滤光片的抑制效果。结果:两种过滤器单独抑制 PPR 的效果均不充分(低于 50%)。由两种类型的滤光片组成的复合光学滤光片可以抑制 PPR,对于 IPS 大约 90%,对于 CRT 光刺激大约 95%。这些复合滤光片不会破坏电视 CRT 发射的色度。结论:这些复合滤光器可能有助于预防光敏感人群因电视引起的癫痫发作。
Objective: Televised images are the most common stimulus for provoking photosensitive seizures in photosensitive persons. To inhibit photosensitive seizures in photosensitive persons who do or do not have epilepsy, the authors sought nonpharmacologic methods for reducing the levels of photic stimulation of televised images. Background: The authors found two types of pathophysiologic mechanisms (wavelength-dependent and quantity of light–dependent mechanisms) for photoparoxysmal responses (PPR). Methods: The authors tested two different types of optical filters, one reflecting long-wavelength red light selectively, which stimulates a wavelength-dependent mechanism, and the other absorbing light in the visible spectrum evenly (neutral density filters). Inhibiting effects of optical filters were studied by conventional intermittent photic stimulation (IPS) using strobe light and novel photic stimulation using flashing cathode ray tubes (CRT). Results: Both filters individually inhibited PPR insufficiently (less than 50%). Compound optical filters, composed of both types of filters, can inhibit the PPR, approximately 90% for IPS and 95% for photic stimulation with CRT. These compound optical filters do not destroy chromaticity of emissions from the television’s CRT. Conclusions: These compound filters may be useful to prevent seizures induced by television in photosensitive persons.