Total synthesis of (±)-hedychilactone B:: Stepwise allenoate diene cycloaddition to prepare trimethyldecalin systems
Total synthesis of (±)-hedychilactone B:: Stepwise allenoate diene cycloaddition to prepare trimethyldecalin systems
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DOI：
10.1021/ol062811z
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发表时间：
2007-02-01
期刊：
影响因子：
5.2
通讯作者：
Murakami, Masayuki
中科院分区：
文献类型：
--
作者：
Jung, Michael E.;Murakami, Masayuki
The total synthesis of the diterpene hedychilactone B 1 is reported. The exo adduct 4x, the major product of the stepwise [4+2] cycloaddition of the diene 2 and the allenoate 3, has been converted into 1 via 7 steps, among them a key nonconjugative hydrolysis of a gamma-methylene silyl enol ether and an E-selective olefination.
