Interactions between CdTe quantum dots and plasma proteins: kinetics, thermodynamics and molecular structure changes
Interactions between CdTe quantum dots and plasma proteins: kinetics, thermodynamics and molecular structure changes
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CdTe 量子点与血浆蛋白之间的相互作用：动力学、热力学和分子结构变化
DOI：
10.1016/j.colsurfb.2020.110881
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Peili Huang
中科院分区：
文献类型：
--
作者：
Yue Hu;Huiling Li;Peijun Meng;Kexin Li;Yamin Xiong;Shuhua Zhang;Ying Yang;Aihong Yin;Peili Huang
环境颗粒物，特别是超细颗粒物（纤溶酶原（PLG）>凝血酶（TM）>金属硫蛋白-II（MT-II）>人血清白蛋白（HSA））。这种相互作用主要归因于疏水力和相互作用发生的自发性，FIB和PLG的蛋白质二级结构发生了显著变化。在这项研究中获得的信息可能揭示量子点对心血管系统的潜在毒性。
Environmental particulate matter, especially ultrafine particles ( plasminogen (PLG) > thrombin (TM) > metallothionein-II (MT-II) > human serum albumin (HSA). The interaction was primarily attributed to hydrophobic forces and the spontaneity of the occurrence of the interaction, and the protein secondary structures of FIB and PLG were changed significantly. The information gained in this study might shed light on the potential toxicity of QDs to the cardiovascular system.