A naphthalene-quinoline based chemosensor for fluorescent "turn-on" and absorbance-ratiometric detection of Al3+ and its application in cells imaging.
A naphthalene-quinoline based chemosensor for fluorescent "turn-on" and absorbance-ratiometric detection of Al3+ and its application in cells imaging.
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DOI：
10.1016/j.saa.2018.07.039
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发表时间：
2018-12
期刊：
影响因子：
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通讯作者：
Shuang Zeng;Shijie Li;Xue-Jiao Sun;Ming-Qiang Li;Yu-Qing Ma;Zhi-Yong Xing;Jinlong Li
中科院分区：
文献类型：
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作者：
Shuang Zeng;Shijie Li;Xue-Jiao Sun;Ming-Qiang Li;Yu-Qing Ma;Zhi-Yong Xing;Jinlong Li
制备了一种新型的萘-喹啉化学传感器L，在DMF/H2O（v/v，1/9）体系中，基于ESIPT和CHEF的联合作用机制，L对Al 3+具有明显的荧光增强（335倍）和比率检测特性，表现出良好的选择性和灵敏度。通过Job 'sPlot、FT-IR、HNMR和HRMS分析，详细研究了L对Al ~（3+）的识别行为。该方法对Al ~（3+）的检出限为3.67 × 10 - 8 M. L，已成功应用于真实的样品检测和分子逻辑门的构建。此外，L还具有较低的细胞毒性和良好的成像特性，可用于检测细胞HSC中的Al 3+。
A new naphthalene-quinoline based chemosensorLwas prepared and structurally characterized.Lexhibited excellent selectivity and sensitivity to Al3+through distinct fluorescence enhancement (335-fold) and ratiometric detection in DMF/H2O (v/v, 1/9) based on the combined mechanisms of ESIPT and CHEF. The recognizing behavior ofLtoward Al3+had been investigated in detail through Job's Plot, FT-IR, HNMR, and HRMS analysis. The limit of detection (LOD) for Al3+was as low as and 3.67 × 10−8M.Lwas successfully applied in real sample detection and construction of molecular logic gate. Moreover,Lwas verified to be of low cytotoxicity and good imaging characteristics for the detection of Al3+in cells HSC.