Pain as a predictor and consequence of tobacco abstinence effects amongst African American smokers.
Pain as a predictor and consequence of tobacco abstinence effects amongst African American smokers.
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DOI：
10.1037/abn0000367
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发表时间：
2018-10
影响因子：
4.6
通讯作者：
Leventhal AM
中科院分区：
文献类型：
--
作者：
Bello MS;McBeth JF;Ditre JW;Kirkpatrick MG;Ray LA;Dunn KE;Leventhal AM
非裔美国人在吸烟和慢性疼痛方面存在健康差异。鉴于尼古丁具有镇痛特性，急性疼痛的增加可能是烟草戒断综合征的一种表现，特别是在患有慢性疼痛的非裔美国吸烟者中。这份报告是对正在进行的一项研究的数据进行的二次分析，该研究是关于非裔美国人吸烟者实验室来源的烟草戒断表型的个体差异。我们测试了整夜戒烟是否会增加急性疼痛，以及戒烟引起的急性疼痛变化是否与戒烟的其他表达相关，并在慢性疼痛吸烟者中放大。非裔美国人吸烟者（N = 214; 10+ cig/天）参加了基线访视（报告慢性疼痛时）和两个平衡实验阶段（随意吸烟vs. 16小时戒烟）。在两个实验阶段，自我报告的急性疼痛和其他戒烟症状的措施。戒烟显着增加急性疼痛（d = 0.17，p = 0.01）。戒断引起的急性疼痛变化与戒断引起的负面情绪变化（r = 0.15，p = 0.02）、吸烟欲望变化（r = 0.13，p = 0.05）和复合尼古丁戒断症状变化（r = 0.13，p = 0.06）之间的相关性很小，经多次测试校正后不显著，表明急性疼痛和其他烟草戒断表达的戒断引起的变化中的表型变异在很大程度上是独立的。慢性疼痛的基线水平预示着在实验过程中更大的戒断引起的疼痛放大（βs = 0.29 = 0.31; ps <0.001）。在非裔美国人吸烟者中，主要是那些患有慢性疼痛的人，在夜间戒烟（与饱食相比）后，急性疼痛更大。解决烟草成瘾科学，治疗和健康公平规划的痛苦值得考虑。这项研究是第一个对照实验调查的交叉疼痛，吸烟，和烟草戒断综合征的非洲裔美国人吸烟者。我们的研究结果表明，急性疼痛可能是一个独特的表型表达的烟草禁欲，是不成比例地表达在非洲裔美国人吸烟者与慢性疼痛。
African Americans are subject to health disparities in smoking and chronic pain. Given that nicotine has analgesic properties, increases in acute pain may be an expression of the tobacco abstinence syndrome, particularly among African American smokers with chronic pain. This report is a secondary analysis of data from an ongoing study of individual differences in laboratory-derived tobacco abstinence phenotypes in African American smokers. We tested whether overnight smoking abstinence increased acute pain and whether abstinence-induced changes in acute pain were correlated with other expressions of tobacco abstinence and amplified among smokers with chronic pain. African American smokers (N = 214; 10+ cig/day) attended a baseline visit (when chronic pain was reported), and two counterbalanced experimental sessions (ad libitum smoking vs. 16-hr smoking abstinence). At both experimental sessions, measures of self-reported acute pain and other tobacco abstinence symptoms were administered. Smoking abstinence significantly increased acute pain (d = .17, p = .01). Correlations between abstinence-induced changes in acute pain and abstinence-induced changes in negative affect, r = .15, p = .02, smoking urges, r = .13, p = .05, and composite nicotine withdrawal symptoms, r = .13, p = .06, were small and nonsignificant after correction for multiple tests, indicating that phenotypic variation in abstinence-provoked changes in acute pain and other tobacco abstinence expressions were largely independent. Baseline levels of chronic pain predicted greater abstinence-induced pain amplification at experimental sessions (βs = .29 =.31; ps < .001). Acute pain is greater following overnight tobacco abstinence (vs. satiation) among African American smokers, predominantly among those with chronic pain. Addressing pain in tobacco addiction science, treatment, and health equity programming warrants consideration. This study is the first controlled experimental investigation of the intersection of pain, smoking, and the tobacco abstinence syndrome in African American smokers. Our findings suggest that acute pain may be a distinct phenotypic expression of tobacco abstinence that is disproportionately expressed among African American smokers with chronic pain.
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影响因子：
1.6
作者：
Behrend, Caleb;Schonbach, Etienne;Rechtine, Glenn
通讯作者：
Rechtine, Glenn
DOI：
10.1682/jrrd.2006.05.0051
发表时间：
2007-01-01
影响因子：
--
作者：
Jones, Katherine R.;Vojir, Carol P.;Fink, Regina
通讯作者：
Fink, Regina
影响因子：
4.4
作者：
Choi, WS;Okuyemi, KS;Ahluwalia, JS
通讯作者：
Ahluwalia, JS
影响因子：
7.4
作者：
Ditre JW;Heckman BW;Zale EL;Kosiba JD;Maisto SA
通讯作者：
Maisto SA
DOI：
10.1007/s12160-016-9769-9
发表时间：
2016-06
期刊：
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
影响因子：
--
作者：
Ditre JW;Kosiba JD;Zale EL;Zvolensky MJ;Maisto SA
通讯作者：
Maisto SA