Hollow colloidosomes with an enzyme confined in a porous shell as Pickering interfacial biocatalysts for efficient bioconversions

Hollow colloidosomes with an enzyme confined in a porous shell as Pickering interfacial biocatalysts for efficient bioconversions
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空心胶体体与限制在多孔壳中的酶作为皮克林界面生物催化剂,用于有效的生物转化

DOI:
10.1039/d0gc02999h
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发表时间:
2021-01-21
期刊:
影响因子:
9.8
通讯作者:
Meng, Tao
Meng, Tao
中科院分区:
化学1区
文献类型:
--
作者:
Sun, Mengmeng;Yin, Wei;Meng, Tao

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Lipase-loaded hollow colloidosomes are prepared for Pickering interfacial biocatalysis (PIB). Unlike in other systems, colloidosomes are self-assembled by lipases and silica nanoparticles, achieving a high enzyme-loading process without chemical cross-linking, and can stabilize Pickering emulsion due to the amphiphilic lipase confined in the porous shell. Remarkably, the enzyme encapsulation rate is 95.2%, which is better than other enzyme-loaded carriers in PIB reported so far. This system maintains 80.4% of the initial enzyme activity after 10 cycles, which provides a powerful and green platform for interfacial biocatalysis.