Bioactive mechanism of Porphyromonas gingivalis lipid A
Bioactive mechanism of Porphyromonas gingivalis lipid A
复制标题
DOI：
10.1111/j.1600-0757.2009.00343.x
复制
发表时间：
2010-01-01
影响因子：
18.6
通讯作者：
Yagi, Takakazu
中科院分区：
文献类型：
--
作者：
Ogawa, Tomohiko;Yagi, Takakazu
本文提供了牙龈卟啉单胞菌脂质A的化学和生物学特性的信息。它说脂多糖的脂质A部分是生物活性中心，它通过在肠道革兰氏阴性菌中发现的Toll样受体2作用于宿主细胞。本文还对牙龈卟啉单胞菌脂质A进行了分离纯化，表明其化学结构为三个脂肪酸残基组成的脂蛋白。
The article provides information on the chemical and biological properties of Porphyromonas gingivalis lipid A. It says that the lipid A part of lipopolysaccharide is the biologically active center, which acts on the host cells through a toll-like receptor 2 that found in enteric gram-negative bacteria. It also mentions that P. gingivalis lipid A was separated and purified, which shows its chemical structure to be lipoprotein consists of three fatty acid residue.