Free-breathing ultrashort echo time lung magnetic resonance imaging using stack-of-spirals acquisition: A feasibility study in oncology patients
Free-breathing ultrashort echo time lung magnetic resonance imaging using stack-of-spirals acquisition: A feasibility study in oncology patients
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DOI：
10.1016/j.mri.2018.05.002
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发表时间：
2018-09-01
影响因子：
2.5
通讯作者：
Kim, Yang Soo
中科院分区：
文献类型：
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作者：
Cha, Min Jae;Park, Hyun Jeong;Kim, Yang Soo
目的：探讨肺磁共振成像（MRI）的诊断准确性与自由呼吸三维超短回波时间扰相梯度回波序列使用堆栈的螺旋采集（螺旋3D UTE）在3 T的肿瘤patients.Methods肺结节检测：机构审查委员会批准了这项回顾性研究。在2017年6月至9月期间，32名肿瘤患者接受了肺的自由呼吸螺旋3D UTE和薄层胸部计算机断层扫描（CT），以进行肺转移检查。由两名评审员对可见肺血管、支气管、纵隔和螺旋3D UTE的整体图像质量进行半定量分析; CT用作参考标准。结节存在的概率也assessed.Results：平均采集时间的螺旋3D UTE为327秒（范围，300-465秒）。在螺旋3D UTE上，肺血管和支气管几乎一致可见，直至亚亚段分支水平（分别为96.9% [31/32]和90.6% [29/32]）。> 90%的螺旋3D UTE图像具有可接受或良好的纵隔评价; > 80%具有良好或优秀的总体图像质量。CT在13例患者中识别出50个结节（6.1 ± 5.9 mm）;螺旋3D UTE的总体结节检出率为86%（43/50）。结论：自由呼吸螺旋3D UTE对肺结节的检出具有较高的敏感性，扫描时间合理，图像质量可接受，可作为肿瘤患者CT的潜在替代方法。
Objectives: To investigate the diagnostic accuracy of lung magnetic resonance imaging (MRI) with a free breathing three-dimensional ultrashort echo time spoiled gradient echo sequence using a stack-of-spirals acquisition (spiral 3D UTE) for pulmonary nodule detection at 3 T in oncology patients.Methods: The institutional review board approved this retrospective study. Between June and September of 2017, 32 oncology patients underwent both free-breathing spiral 3D UTE of the lungs and thin-section chest computed tomography (CT) for pulmonary metastasis workups. Semiquantitative analyses of the visible pulmonary vessels, bronchi, mediastinum, and overall image quality on spiral 3D UTE were assessed by two reviewers; CT was used as the reference standard. The probability of nodule presence also was assessed.Results: The mean acquisition duration of the spiral 3D UTE was 327 s (range, 300-465 s). The pulmonary vessels and bronchi were visible nearly consistently up to the sub-sub-segmental branch levels on spiral 3D UTE (96.9% [31/32] and 90.6% [29/32], respectively). > 90% of the spiral 3D UTE images had an acceptable or good mediastinal evaluation; > 80% had good or excellent overall image quality. Fifty nodules (6.1 +/- 5.9 mm) were identified in 13 patients on CT; the overall nodule detection rate of spiral 3D UTE was 86% (43/50). All 20 nodules 5 mm in diameter were identified on spiral 3D UTE (100%).Conclusions: Free-breathing spiral 3D UTE had high sensitivity for the detection of pulmonary nodules, a reasonable scan duration, and acceptable image quality, which may make it a potential alternative to CT for oncology patients.