Is there a difference between women and men in characteristics and outcome after in hospital cardiac arrest?

Is there a difference between women and men in characteristics and outcome after in hospital cardiac arrest?
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DOI:
10.1016/s0300-9572(00)00342-7
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发表时间:
2001-04-01
期刊:
影响因子:
6.5
通讯作者:
Lindkvist, J
Lindkvist, J
中科院分区:
医学2区
文献类型:
--
作者:
Herlitz, J;Rundqvist, S;Lindkvist, J

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目的:描述女性和男性院内心脏骤停患者的特点和结局。方法:在瑞典哥德堡Sahlgrenska医院召集心肺复苏(CPR)小组,记录所有在3年期间发生院内心脏骤停的患者,并根据特征和结果进行前瞻性描述。结果:有557名患者在住院期间心脏骤停,CPR小组得到了警报。其中,217人(39%)为女性。女性与男性不同,女性早期心肌梗死、心绞痛、肾脏疾病的患病率较低,而风湿病的患病率较高。在心脏骤停的病因方面,47%的男性和48%的女性被判断为已确认或可能患有AMT。室颤/室性心动过速(VF/VT)男性多于女性(57vs.41%;P<0.001),而女性无脉搏电活动(30vs.15%:P<0.0001)。脑功能分类(CPC)-出院时的得分在男性和女性之间没有差异。在女性中,36.4%的人存活到出院,而在男性(NS)中,这一比例为38.0%。VF/VT存活率女性为64.3%,男性为52.7%(NS)。在校正基线上的差异时,女性与男性相比,调整后的活着出院的优势比为1.66(95%可信区间为1.06-2.62;P=0.028)。结论:有39%的住院心脏骤停患者得到了CPR小组的警告。都是女人。女性在室颤、室上性心动过速中的发生率低于男性。在基线上修正了不同之处之后。女性的性别与存活率的小幅改善有关。(C)2001爱思唯尔爱尔兰科学有限公司。保留所有权利。
Aim: To describe the characteristics and outcome among patients suffering from an in-hospital cardiac arrest in women and men. Methods: All patients who suffered an in-hospital cardiac arrest during a 3 year period in Sahlgrenska Hospital Goteborg, Sweden, where the cardiopulmonary resuscitation (CPR) team was called, were recorded and described prospectively in terms of characteristics and outcome. Results: There were 557 patients suffering in-hospital cardiac arrest in whom the CPR-team was alerted. Among them, 217 (39%) were women. Women differed from men having a lower prevalence of earlier myocardial infarction, angina pectoris, renal disease and a higher prevalence of rheumatic disease. In terms of aetiology of the cardiac arrest, 47% men and 48% women were judged to have had a confirmed or possible AMT. More men than women were found in ventricular fibrillation/ventricular tachycardia (VF/VT) (57 vs. 41%; P < 0.001), whereas more women were found in pulseless electrical activity (30 vs. 15%: P < 0.0001). Cerebral performance categories (CPC)-score at discharge did not differ between men and women. Among women, 36.4%;, survived to discharge as compared with 38.0%;, among men (NS). Survival from VF/VT was 64.3% in women and 52.7% in men (NS). When correcting for dissimilarities at baseline, the adjusted odd ratio for being discharged alive from hospital among women as compared with men was 1.66 (95% confidence limit 1.06-2.62; P = 0.028). Conclusion: Thirty nine percent of patients suffering in-hospital cardiac arrest for whom the CPR-team was alerted. were women. Women were less frequently found in VF;VT than men. After correcting for dissimilarities at baseline. female gender was associated with a small improvement in survival. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.