Monitoring stimulated Raman scattering with photoacoustic detection
Monitoring stimulated Raman scattering with photoacoustic detection
复制标题
DOI：
10.1364/ol.36.001233
复制
发表时间：
2011-04-01
期刊：
影响因子：
3.6
通讯作者：
Thomas, Robert J.
中科院分区：
文献类型：
--
作者：
Yakovlev, Vladislav V.;Noojin, Gary D.;Thomas, Robert J.
实验证明了高频超声检测通过拉曼激发来监测能量沉积到分子系统中的过程的能力。结果表明，受激拉曼散射产生的超声信号与光信号成正比。超声检测提供了一种简单的方法来区分激光诱导的击穿，并允许在直接光学检测不可用的情况下对受激拉曼散射过程进行量化。此外，如果产生的光声信号足够强，它可以用于深部组织的受激拉曼成像。(C) 2011美国光学学会
A capability of high-frequency ultrasound detection to monitor the process of energy deposition into a molecular system via Raman excitation is experimentally demonstrated. It is shown that the generated ultrasound signal is directly proportional to the optical signal generated in stimulated Raman scattering. Ultrasound detection provides a simple way to discriminate against laser-induced breakdown and allows for the quantification of the stimulated Raman scattering process where direct optical detection is not available. Additionally, it can be used for stimulated Raman imaging in deep tissue, provided that the generated photoacoustic signal is sufficiently strong. (C) 2011 Optical Society of America