3D printed microfluidic circuitry via multijet-based additive manufacturing.
3D printed microfluidic circuitry via multijet-based additive manufacturing.
复制标题
DOI：
10.1039/c5lc01389e
复制
发表时间：
2016-02-21
期刊：
影响因子：
6.1
通讯作者：
Lin L
中科院分区：
文献类型：
--
作者：
Sochol RD;Sweet E;Glick CC;Venkatesh S;Avetisyan A;Ekman KF;Raulinaitis A;Tsai A;Wienkers A;Korner K;Hanson K;Long A;Hightower BJ;Slatton G;Burnett DC;Massey TL;Iwai K;Lee LP;Pister KS;Lin L
集成流体处理器的小型化为化学和生物领域提供了广泛的好处，然而传统的单片微加工方法为流体操作器的规模化提供了许多障碍。最近，研究人员已经研究了使用增材制造或“三维（3D）打印”技术-主要是立体光刻-作为构建亚毫米级流体元件的有前途的替代方案。然而，一个挑战是，目前的立体光刻方法缺乏同时打印牺牲支撑材料的能力，这限制了这种方法的几何通用性。在这项工作中，我们研究了多射流建模（或者，多射流打印）的使用-一种逐层，多材料喷墨工艺-用于3D打印几何复杂，但功能上有利的流体组件，包括静态和动态物理元素。我们研究了一个基本类的3D打印微流体操作员，包括流体电容器，流体二极管和流体晶体管。此外，我们评估了通过元件参数的几何修改来推进集成流体系统片上自动化的潜力。三维流体电容器的理论和实验结果表明，从平面膜片结构过渡到非平面膜片结构可以提高元件性能。3D打印射流二极管的流动整流实验表明，二极管的二极管度为80.6±1.8。基于几何增益增强的3D打印流体晶体管的压力增益为3.01±0.78。与附加的增材制造方法一致，使用数字可转移的流体部件3D模型与商用3D打印机相结合，可以将流体路由能力扩展到核心工程社区以外的领域的研究人员。
The miniaturization of integrated fluidic processors affords extensive benefits for chemical and biological fields, yet traditional, monolithic methods of microfabrication present numerous obstacles for the scaling of fluidic operators. Recently, researchers have investigated the use of additive manufacturing or “three-dimensional (3D) printing” technologies – predominantly stereolithography – as a promising alternative for the construction of submillimeter-scale fluidic components. One challenge, however, is that current stereolithography methods lack the ability to simultaneously print sacrificial support materials, which limits the geometric versatility of such approaches. In this work, we investigate the use of multijet modelling (alternatively, polyjet printing) – a layer-by-layer, multi-material inkjetting process – for 3D printing geometrically complex, yet functionally advantageous fluidic components comprised of both static and dynamic physical elements. We examine a fundamental class of 3D printed microfluidic operators, including fluidic capacitors, fluidic diodes, and fluidic transistors. In addition, we evaluate the potential to advance on-chip automation of integrated fluidic systems via geometric modification of component parameters. Theoretical and experimental results for 3D fluidic capacitors demonstrated that transitioning from planar to non-planar diaphragm architectures improved component performance. Flow rectification experiments for 3D printed fluidic diodes revealed a diodicity of 80.6 ± 1.8. Geometry-based gain enhancement for 3D printed fluidic transistors yielded pressure gain of 3.01 ± 0.78. Consistent with additional additive manufacturing methodologies, the use of digitally-transferrable 3D models of fluidic components combined with commercially-available 3D printers could extend the fluidic routing capabilities presented here to researchers in fields beyond the core engineering community.