Impact of Immune Cells in the Tumor Microenvironment of Prostate Cancer Metastasis.
Impact of Immune Cells in the Tumor Microenvironment of Prostate Cancer Metastasis.
复制标题
DOI：
10.3390/life13020333
复制
发表时间：
2023-01-26
期刊：
影响因子：
3.2
通讯作者：
Liou, Geou-Yarh
中科院分区：
文献类型：
--
作者：
Messex, Justin K.;Liou, Geou-Yarh
Prostate cancer is the most prevalent type of cancer in senior American men. Currently, the five-year survival rate after the initial diagnosis of prostate cancer is close to 100%. However, it is also the second leading cause of cancer death in senior men due to the dissemination of prostate cancer cells outside of the prostate causing growth in other organs, known as metastatic prostate cancer. The tumor microenvironment (TME) plays a critical role in the development, progression and metastasis of prostate cancer. One of the major components of the TME contains various types of immune cells, often recruited by cancer cells to the cancer formation areas. The interactions among prostate cancer cells and the infiltrating immune cells affect the outcome of prostate cancer. Here, we summarize the mechanisms various infiltrating immune cells use to regulate prostate cancer metastasis and possibly lead to the development of treatment strategies. Furthermore, the information here may also give rise to preventative strategies that focus on targeting the TME of prostate cancer patients.
登录
查看更多内容
影响因子：
11.2
作者：
Ancey PB;Contat C;Boivin G;Sabatino S;Pascual J;Zangger N;Perentes JY;Peters S;Abel ED;Kirsch DG;Rathmell JC;Vozenin MC;Meylan E
通讯作者：
Meylan E
影响因子：
11.1
作者：
Izumi K;Fang LY;Mizokami A;Namiki M;Li L;Lin WJ;Chang C
通讯作者：
Chang C
影响因子：
50.3
作者：
Kfoury Y;Baryawno N;Severe N;Mei S;Gustafsson K;Hirz T;Brouse T;Scadden EW;Igolkina AA;Kokkaliaris K;Choi BD;Barkas N;Randolph MA;Shin JH;Saylor PJ;Scadden DT;Sykes DB;Kharchenko PV;as part of the Boston Bone Metastases Consortium
通讯作者：
as part of the Boston Bone Metastases Consortium
影响因子：
28.2
作者：
Gunderson AJ;Kaneda MM;Tsujikawa T;Nguyen AV;Affara NI;Ruffell B;Gorjestani S;Liudahl SM;Truitt M;Olson P;Kim G;Hanahan D;Tempero MA;Sheppard B;Irving B;Chang BY;Varner JA;Coussens LM
通讯作者：
Coussens LM
影响因子：
28.2
作者：
Lee KE;Spata M;Bayne LJ;Buza EL;Durham AC;Allman D;Vonderheide RH;Simon MC
通讯作者：
Simon MC