Uncontrolled blood pressure and risk of sleep apnea among blacks: findings from the Metabolic Syndrome Outcome (MetSO) study.
Uncontrolled blood pressure and risk of sleep apnea among blacks: findings from the Metabolic Syndrome Outcome (MetSO) study.
复制标题
黑人血压不受控制和睡眠呼吸暂停的风险：代谢综合征结果 (MetSO) 研究的结果。
DOI：
10.1038/jhh.2015.78
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发表时间：
2016
影响因子：
2.7
通讯作者：
Jean-Louis,G
中科院分区：
文献类型：
--
作者：
Seixas,A;Ravenell,J;Williams,NJ;Williams,SK;Zizi,F;Ogedegbe,G;Jean-Louis,G
血压 (BP) 不受控制与阻塞性睡眠呼吸暂停 (OSA) 风险增加有关。然而，很少有研究评估这种关系对患有代谢综合征 (MetS) 的黑人的影响。本研究的数据收集自参加代谢综合征结果研究的 1035 名黑人（平均年龄 = 62±13 岁）。呼吸暂停风险评估系统得分≥6 的患者被认为有 OSA 风险。在样本中，77.1% 的人患有从低到高的 OSA 风险，92.3% 的人患有高血压，其中 16.8% 的血压水平不受控制。分析还显示，60.4%的人患有糖尿病，8.9%的人有中风史，74.3%的人有血脂异常，69.8%的人肥胖，30.9%的人有心脏病史。采用逻辑回归分析来研究不受控制的血压与 OSA 风险之间的关联，同时调整已知的协变量。研究结果表明，血压不受控制会使 OSA 风险的几率增加两倍（优势比 = 2.02，95% 置信区间 = 1.18–3.48，P< 0.05）。总之，我们的研究结果表明，在黑人中，血压不受控制与 OSA 风险增加一倍相关，这表明患有 MetS 和血压不受控制的人应该筛查 OSA 的存在。
Uncontrolled blood pressure (BP) is linked to increased risk of obstructive sleep apnea (OSA). However, few studies have assessed the impact of this relationship among blacks with metabolic syndrome (MetS). Data for this study were collected from 1035 blacks (mean age= 62±13 years) enrolled in the Metabolic Syndrome Outcome study. Patients with a score⩾ 6 on the Apnea Risk Evaluation System were considered at risk for OSA. Of the sample, 77.1% were low-to-high OSA risk and 92.3% were hypertensive, of which 16.8% had uncontrolled BP levels. Analysis also showed that 60.4% were diabetic, 8.9% had a stroke history, 74.3% had dyslipidemia, 69.8% were obese and 30.9% had a history of heart disease. Logistic regression analyses were employed to investigate associations between uncontrolled BP and OSA risk, while adjusting for known covariates. Findings showed that uncontrolled BP independently increased the odds of OSA risk twofold (odds ratio= 2.02, 95% confidence interval= 1.18–3.48, P< 0.05). In conclusion, our findings show that uncontrolled BP was associated with a twofold greater risk of OSA among blacks, suggesting that those with MetS and who have uncontrolled BP should be screened for the presence of OSA.