Simultaneous measurement of hepatic and splenic stiffness using MR elastography: preliminary experience.
Simultaneous measurement of hepatic and splenic stiffness using MR elastography: preliminary experience.
复制标题
DOI:
10.1007/s00261-014-0255-1
复制
发表时间:
2015-04
影响因子:
--
通讯作者:
Taouli, Bachir
中科院分区:
文献类型:
--
作者:
Dyvorne, Hadrien A.;Jajamovich, Guido H.;Besa, Cecilia;Cooper, Nancy;Taouli, Bachir
To compare MR elastography (MRE) using a single and a dual driver excitation for the quantification of hepatic and splenic stiffness (HS and SS), and to investigate the performance of HS and SS measured with single or dual driver excitation for the detection of liver cirrhosis in subjects with liver disease. This prospective HIPAA compliant and IRB approved study involved 49 subjects who underwent MRE at 3.0T, comparing 3 different acquisition methods (single driver on the liver, single driver on the spleen and dual driver acoustic excitation). A Mann-Whitney test was used to assess changes in stiffness values. Bland-Altman analysis was used to compare single and dual driver configurations for each organ. Performance for detection of liver cirrhosis was assessed using ROC analysis. Pearson correlation was used to estimate the dependence of HS and SS on spleen size. There were 40 noncirrhotic and 9 cirrhotic patients. There was good agreement between stiffness values measured with a single or a dual driver (Bland-Altman limits of agreement -14.3%–18.9 % and -18.1%–29.7 %, CV 6.4 % and 9.4 %, for HS and SS respectively). HS and SS were higher in subjects with liver cirrhosis (p <0.001), with excellent detection performance (AUROC range 0.87–0.93). SS correlated strongly with spleen size (r=0.69, p<0.001) while HS showed weak correlation (r=0.38, p=0.006). Using a dual acoustic driver configuration, hepatic and splenic stiffness can be simultaneously estimated with good concordance with single driver measurement.
登录
查看更多内容
影响因子:
29.4
作者:
Huwart, Laurent;Sempoux, Christine;Van Beers, Bernard E.
通讯作者:
Van Beers, Bernard E.
影响因子:
29.4
作者:
Colecchia, Antonio;Montrone, Lucia;Festi, Davide
通讯作者:
Festi, Davide
影响因子:
5.9
作者:
Ronot, Maxime;Lambert, Simon;Garteiser, Philippe
通讯作者:
Garteiser, Philippe
影响因子:
5.1
作者:
Escorsell, A;Garcia-Pagan, J C;Bosch, J
通讯作者:
Bosch, J
影响因子:
29.4
作者:
Moitinho, E;Escorsell, N;Bosch, J
通讯作者:
Bosch, J