Convergence of vestibular and visual self-motion signals in an area of the posterior sylvian fissure.
Convergence of vestibular and visual self-motion signals in an area of the posterior sylvian fissure.
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DOI：
10.1523/jneurosci.1266-11.2011
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发表时间：
2011-08-10
期刊：
影响因子：
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通讯作者：
Angelaki DE
中科院分区：
文献类型：
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作者：
Chen A;DeAngelis GC;Angelaki DE
视觉运动信息（光流）和前庭信号的会聚对于自我运动感知是重要的，并且已经在背侧内侧上级颞（MSTd）和腹侧顶内（VIP）区域中观察到这种会聚。与此相反，顶叶岛前庭皮质（PIVC），侧裂的皮质前庭区，是不响应的光流。在这里，我们探讨猕猴视觉后外侧裂区（VPS）的视流和前庭会聚。该区域位于外侧裂的后端，与PIVC紧密相连，并接受MSTd的投射。我们发现超过三分之一的VPS细胞具有强大的光流和前庭调谐，所有运动方向都被均匀地表示。然而，视觉和前庭方向偏好的翻译大多是相反的，不像在区域MSTd中，大致相等比例的神经元具有一致或相反的视觉/前庭方向偏好。总体而言，VPS的光流反应弱于MSTd，而前庭反应VPS强于MSTd。当视觉和前庭刺激一起呈现时，VPS反应由前庭信号主导，与MSTd相反，其中光流调谐通常占主导地位。这些结果表明，VPS是近端MSTd的前庭处理，但远端MSTd的光流处理。鉴于VPS中具有相反视觉/前庭标题偏好的神经元的优势，该区域可能在多感官标题感知中不起主要作用。
Convergence of visual motion information (optic flow) and vestibular signals is important for self-motion perception, and such convergence has been observed in the dorsal medial superior temporal (MSTd) and ventral intraparietal (VIP) areas. In contrast, the parieto-insular vestibular cortex (PIVC), a cortical vestibular area in the sylvian fissure, is not responsive to optic flow. Here we explore optic flow and vestibular convergence in the visual posterior sylvian area (VPS) of macaque monkeys. This area is located at the posterior end of the sylvian fissure, is strongly interconnected with PIVC, and receives projections from MSTd. We found robust optic flow and vestibular tuning in more than one-third of VPS cells, with all motion directions being represented uniformly. However, visual and vestibular direction preferences for translation were mostly opposite, unlike in area MSTd where roughly equal proportions of neurons have visual/vestibular heading preferences that are congruent or opposite. Overall, optic flow responses in VPS were weaker than those in MSTd, whereas vestibular responses were stronger in VPS than in MSTd. When visual and vestibular stimuli were presented together, VPS responses were dominated by vestibular signals, in contrast to MSTd, where optic flow tuning typically dominates. These findings suggest that VPS is proximal to MSTd in terms of vestibular processing, but distal to MSTd in terms of optic flow processing. Given the preponderance of neurons with opposite visual/vestibular heading preferences in VPS, this area may not play a major role in multisensory heading perception.