THE PREVALENCE OF PAIN IN A PEDIATRIC AND YOUNG-ADULT CANCER POPULATION

THE PREVALENCE OF PAIN IN A PEDIATRIC AND YOUNG-ADULT CANCER POPULATION
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DOI:
10.1016/0304-3959(87)90180-1
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发表时间:
1987-04-01
期刊:
影响因子:
7.4
通讯作者:
MISER, JS
MISER, JS
中科院分区:
医学1区
文献类型:
--
作者:
MISER, AW;DOTHAGE, JA;MISER, JS

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在国家癌症研究所儿科分支治疗的儿童和年轻人恶性肿瘤患者中,对疼痛的患病率和性质进行了为期6个月的评估。在161个住院日和195个门诊就诊期间,对139名患者进行了评价。在医院评估的患者中约有50%和在门诊评估的患者中约有25%在评估时出现一定程度的疼痛。治疗相关疼痛在住院患者和门诊患者中占主导地位;住院患者经历的疼痛中只有三分之一和门诊患者经历的疼痛中不到20%是由于肿瘤引起的。肿瘤疼痛主要是由于骨侵犯。为了控制疼痛患者的疼痛,一半的住院患者和三分之一的门诊患者使用麻醉性镇痛药。总体疼痛控制良好,0-100 mm量表上的中位视觉模拟量表评分为26 mm。在研究期间,7名患者在从疼痛部位根除所有已知肿瘤后,被确定患有慢性疼痛超过1年。其中一人接受了大剂量的麻醉剂(每天120毫克的美沙酮),显然与他的潜在痛苦不成比例。
The prevalence and nature of pain in the population of children and young adults with malignancy treated by the Pediatric Branch of the National Cancer Institute were assessed over a 6 month period. One hundred and thiry-nine patients were evaluated during 161 in-patient days and 195 out-patient clinic visits. Approximately 50% of the patients assessed in the hospital and 25% of the patients assessed in the out-patient clinic were found to be experiencing some degree of pain at the time of assessment. Therapy-related pain predominated in both in-patients and out-patients; only one-third of the pain experienced by in-patients and less than 20% of the pain experienced by out-patients was due to tumor. Tumor pain was due primarily to bony invasion. In order to control pain in those individuals experiencing pain, narcotic analgesics were being used by one-half of the in-patients and one-third of the out-patients. Overall pain control was good, with the median visual analogue scale score being 26 mm on a 0-100 mm scale. During the study period 7 patients were identified to have chronic pain for greater than 1 year following eradication of all known tumor from the site of pain. One was receiving massive doses of narcotics (120 mg/day of methadone) apparently out of proportion to his underlying pain.