Child pneumonia - focus on the Western Pacific Region.
Child pneumonia - focus on the Western Pacific Region.
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DOI：
10.1016/j.prrv.2016.07.004
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发表时间：
2017-01
影响因子：
5.8
通讯作者：
Marais BJ
中科院分区：
文献类型：
--
作者：
Nguyen TK;Tran TH;Roberts CL;Graham SM;Marais BJ
在世界范围内，肺炎是婴儿和幼儿（<5岁）死亡的主要原因。我们概述了全球肺炎疾病负担，以及世界不同地区的病原学和管理实践，特别关注世卫组织西太平洋区域。2011年，西太平洋区域估计每儿童年发生0.11起肺炎事件，有61 900名5岁以下儿童死于肺炎。大多数（>75%）肺炎死亡发生在六个国家：柬埔寨、中国、老挝、巴布亚新几内亚、菲律宾和越南。历史上，肺炎链球菌和流感嗜血杆菌是幼儿重症肺炎和肺炎相关死亡的最常见原因，但随着高效结合疫苗的引入和社会经济的发展，这种情况正在发生变化。病毒和非典型细菌的相对贡献似乎在增加，传统的病例管理方法可能需要修改，以适应西太平洋地区结合疫苗的增加。应认真考虑降低风险战略、提高疫苗接种覆盖率、改善低氧血症管理和抗生素管理。
Worldwide, pneumonia is the leading cause of death in infants and young children (aged <5 years). We provide an overview of the global pneumonia disease burden, as well as the aetiology and management practices in different parts of the world, with a specific focus on the WHO Western Pacific Region. In 2011, the Western Pacific region had an estimated 0.11 pneumonia episodes per child-year with 61,900 pneumonia-related deaths in children less than 5 years of age. The majority (>75%) of pneumonia deaths occurred in six countries; Cambodia, China, Laos, Papua New Guinea, the Philippines and Viet Nam. Historically Streptococcus pneumoniae and Haemophilus influenzae were the commonest causes of severe pneumonia and pneumonia-related deaths in young children, but this is changing with the introduction of highly effective conjugate vaccines and socio-economic development. The relative contribution of viruses and atypical bacteria appear to be increasing and traditional case management approaches may require revision to accommodate increased uptake of conjugated vaccines in the Western Pacific region. Careful consideration should be given to risk reduction strategies, enhanced vaccination coverage, improved management of hypoxaemia and antibiotic stewardship.
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DOI：
10.1183/09031936.00199112
发表时间：
2013-12
期刊：
The European respiratory journal
影响因子：
--
作者：
Elemraid MA;Sails AD;Eltringham GJ;Perry JD;Rushton SP;Spencer DA;Thomas MF;Eastham KM;Hampton F;Gennery AR;Clark JE;North East of England Paediatric Respiratory Infection Study Group
通讯作者：
North East of England Paediatric Respiratory Infection Study Group
影响因子：
168.9
作者：
Bhutta, Zulfiqar A.;Das, Jai K.;Black, Robert E.
通讯作者：
Black, Robert E.
影响因子：
3.6
作者：
Brooks, W. Abdullah;Goswami, Doli;Luby, Stephen
通讯作者：
Luby, Stephen
影响因子：
3.7
作者：
Do AH;van Doorn HR;Nghiem MN;Bryant JE;Hoang TH;Do QH;Van TL;Tran TT;Wills B;Nguyen VC;Vo MH;Vo CK;Nguyen MD;Farrar J;Tran TH;de Jong MD
通讯作者：
de Jong MD
影响因子：
3.7
作者：
Chisti, Mohammod Jobayer;Graham, Stephen M.;Salam, Mohammed Abdus
通讯作者：
Salam, Mohammed Abdus