Adequacy of dialysis with tidal and continuous cycling peritoneal dialysis in children

Adequacy of dialysis with tidal and continuous cycling peritoneal dialysis in children
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DOI:
10.1093/ndt/15.9.1438
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发表时间:
2000-09-01
影响因子:
6.1
通讯作者:
Holmberg, C
Holmberg, C
中科院分区:
医学1区
文献类型:
--
作者:
Hölttä, T;Rönnholm, K;Holmberg, C

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背景资料。今天,腹膜透析的主要结果衡量标准是充分性。我们为每个患者寻求最佳的透析方式和处方。1990年引入潮汐透析(TPD)以提高疗效。然而,与TPD的研究一直不一致,在儿童中的结果也是滞后的。对9例5岁以下或8例5岁以上正在或开始维持性腹膜透析(PD)的患者进行研究。患者分别接受TPD和持续循环透析(CCPD),每组6个月。为了优化TPD和CCPD模式,我们记录了血尿素K-t/V、肌酐清除量(CrCl)、腹膜容量、临床检查、生化指标和营养。TPD组平均夜间透析液流量为46.4±-3.7ml/kg/h,CCPD组为32.7+/-4.6ml/kg/h,差异有统计学意义(P
Background. Today the major outcome measure for peritoneal dialysis is adequacy. We seek the optimal dialysis modality and prescription for each patient. Tidal dialysis (TPD) was introduced in 1990 to increase efficacy. However, studies with TPD have been inconsistent, and results in small children are lacking.Methods. Nine patients under and eight patients over 5 years of age who were undergoing or starting maintenance peritoneal dialysis (PD) were studied. Patients were dialysed with TPD and with continuous cycling PD (CCPD), each for 6 months. To optimize TPD and CCPD modalities, we recorded urea K-t/V, creatinine clearance (CrCl), peritoneal membrane capacity, clinical examination, biochemical values and nutrition.Results. The mean nightly dialysate flow rate was significantly higher with TPD than with CCPD (46.4+/-3.7 vs 32.7+/-4.6 ml/kg/h, P