3D printing dental composite resins with sustaining antibacterial ability
3D printing dental composite resins with sustaining antibacterial ability
复制标题
具有持续抗菌能力的3D打印牙科复合树脂
DOI：
10.1007/s10853-018-2801-7
复制
发表时间：
2019-02-01
影响因子：
4.5
通讯作者：
Ren Li
中科院分区：
文献类型：
--
作者：
Liu Sa;Li Kaiwu;Ren Li
3D打印为许多行业带来了革命性的变化，尤其是在牙科领域。然而，牙齿修复体在患者口腔内佩戴时，继发龋的发生率较高。本文通过添加载银埃洛石纳米管（Ag-HNT），开发了一种用于数字光处理3D打印的抗菌立体光刻树脂（SLR）。用透射电镜（TEM）和X射线能谱（EDS）对Ag-HNT的形貌和成分进行了表征。用透射电子显微镜研究了Ag-HNT在SLR中的均匀分布。固化曲线表明，Ag-HNT的加入对复合树脂的光固化行为影响不大。三点弯曲试验表明，加入3%的Ag-HNT后，试样的弯曲强度提高了25%。通过在树脂浸提液中培养变形链球菌，证实了固化的Ag-HNT/SLR的持续抗菌能力。L929细胞在浸提液中培养48 h，CCK-8法检测结果表明复合树脂具有良好的细胞相容性。
3D printing brought revolutionary changes to many industries, especially in the field of dentistry. However, dental restoration has a high incidence of secondary caries when patients wearing in the oral cavity. In this paper, we developed an antibacterial stereolithography resins (SLR) for digital light processing 3D printing by adding Ag-carrying halloysite nanotubes (Ag-HNT). The morphology and component of Ag-HNT were characterized by transmission electron microscope (TEM) and energy-dispersive X-ray spectroscopy. The uniform distribution of Ag-HNT in SLR was investigated by TEM. The curing curve showed that photo-curable behavior of the composite resins was hardly affected by the addition of Ag-HNT. Three-point bending test indicated that bending strength of the samples increased by 25% after addition of 3% Ag-HNT. A continuous antibacterial ability of cured Ag-HNT/SLR was evidenced by culturing streptococcus mutans in the leaching solution of resins. L929 cells were cultured in the leaching solution for 48 h, and the results of CCK-8 assay indicated that the composite resins had good cytocompatibility.