Assessing DNA Damage from Enzyme-Oxidized Single-Walled Carbon Nanotubes.

Assessing DNA Damage from Enzyme-Oxidized Single-Walled Carbon Nanotubes.
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评估酶氧化单壁碳纳米管造成的 DNA 损伤

DOI:
10.1039/c3tx50022e
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发表时间:
2013-11-01
影响因子:
2.1
通讯作者:
Rusling JF
Rusling JF
中科院分区:
医学4区
文献类型:
--
作者:
Pan S;Sardesai NP;Liu H;Rusling JF

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氧化单壁碳纳米管(SWCNT)的过氧化物酶消化首次被证明在潜在的遗传毒性反应中损伤DNA,使用具有和不具有代谢激活的电光阵列。
Peroxidase enzyme digests of oxidized single-wall carbon nanotubes (SWCNT) were shown to damage DNA in potentially genotoxic reactions for the first time using an electro-optical array with and without metabolic activation.