Solid-phase intermolecular radical reactions 2:: Synthesis of C-glycopeptide mimetics via a novel acrylate acceptor

Solid-phase intermolecular radical reactions 2:: Synthesis of C-glycopeptide mimetics via a novel acrylate acceptor
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DOI:
10.1021/ol025846h
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发表时间:
2002-05-16
期刊:
影响因子:
5.2
通讯作者:
Wilden, JD
Wilden, JD
中科院分区:
化学1区
文献类型:
--
作者:
Caddick, S;Hamza, D;Wilden, JD

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[GRAPHICS]A novel tetrafluorophenol-linked acrylate is reported as an activated acceptor for intermolecular radical reactions. Addition of alkyl radicals led to pure products in good yields. We include here the first syntheses of C1- and C6-linked glycosides using a solid-phase radical methodology.