Prevalence of sarcopenic obesity based on newly proposed diagnostic criteria and functional outcomes in older adults undergoing rehabilitation
Prevalence of sarcopenic obesity based on newly proposed diagnostic criteria and functional outcomes in older adults undergoing rehabilitation
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DOI：
10.1016/j.mad.2022.111728
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发表时间：
2022-09-15
影响因子：
5.3
通讯作者：
Fujishima, Ichiro
中科院分区：
文献类型：
--
作者：
Shimizu, Akio;Maeda, Keisuke;Fujishima, Ichiro
2022年，欧洲临床营养与代谢学会（ESPEN）和欧洲肥胖研究协会（EASO）工作组提出了肌肉减少性肥胖的统一诊断标准。然而，没有研究将这些标准适用于亚洲人群或检查使用这些标准诊断的肌肉减少性肥胖的患病率或其与功能结局的相关性。这项回顾性队列研究调查了根据ESPEN和EASO标准诊断的肌肉减少性肥胖患病率及其与1080例接受康复治疗的日本老年患者（平均年龄79.5岁，43.5%为男性）功能结局的相关性。根据上述标准，肌肉减少性肥胖定义为BMI >= 25 kg/m2，体脂百分比（PBF）增加，骨骼肌质量（SMM）减少和握力低。使用各种ESPEN和EASO提出的PBF增加和SMM减少的定义调查了肌源性肥胖的患病率。根据患者在功能独立性测量（Functional Independence Measure，简称FMD）的最小临床重要差异（Minimum Clinical Significant Difference，简称MCID）方面是否改善，对功能结局进行评价。患病率为4.3- 5.3%。肌源性肥胖与MCID成绩无关。根据ESPEN和EASO标准，日本接受康复治疗的老年患者中，肌源性肥胖的患病率较低，与不良功能结局无关。
In 2022, the European Society for Clinical Nutrition and Metabolism (ESPEN) and European Association for the Study of Obesity (EASO) working group proposed uniform diagnostic criteria for sarcopenic obesity. However, no study has adapted these criteria to an Asian population or examined sarcopenic obesity prevalence diagnosed using these criteria or its association with functional outcomes. This retrospective cohort study investigated sarcopenic obesity prevalence diagnosed based on the ESPEN and EASO criteria, and its association with functional outcomes in 1080 older Japanese patients (mean age 79.5 years, 43.5 % male) undergoing rehabilitation. Based on the mentioned criteria, sarcopenic obesity is defined as a BMI >= 25 kg/m(2), increased percent body fat (PBF), reduced skeletal muscle mass (SMM), and low handgrip strength. Sarcopenic obesity prevalence was investigated using various ESPEN- and EASO-proposed definitions of increased PBF and reduced SMM. Functional outcomes were evaluated based on whether patients improved in the minimal clinically important difference (MCID) of the Functional Independence Measure (FIM). The prevalence was 4.3-5.3 %. Sarcopenic obesity was not independently related to FIM MCID achievement. Sarcopenic obesity prevalence-based on the ESPEN and EASO criteria-in older Japanese patients undergoing rehabilitation was low and was not associated with poor functional outcomes.